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Statistical Methods at the Forefront of Biomedical Advances

  • Book
  • © 2023

Overview

Editors:
  1. Yolanda Larriba

    1. Department of Statistics and Operations Research, University of Valladolid, Valladolid, Spain

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  • Focuses on novel statistical methods to address new biomedical challenges
  • Presents the necessary mathematical rigour with an approachable writing style
  • Describes open source code so readers can reproduce the statistical methods in the clinic

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About this book

This book presents novel statistics methods and reproducible software that helps to solve challenging problems in biomedicine. Specifically, it consists of a collection of 11 chapters contributed by some of the leading experts in the mathematical and statistical field which address new challenges in very disparate biomedical areas, such as genomics, cancer, circadian biology, microbiome, mental disorders, and more. The mathematical rigor is written in a user-friendly way to serve a general biomedical audience ranging from trainees or students to doctors, as well as scientific researchers, university departments, and PhD students.

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xi
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  2. Multivariate Disease Mapping Models to Uncover Hidden Relationships Between Different Cancer Sites

    • Aritz Adin, Tomás Goicoa, María Dolores Ugarte
    Pages 1-20

  3. Machine Learning Applied to Omics Data

    • Aida Calviño, Almudena Moreno-Ribera, Silvia Pineda
    Pages 21-43

  4. Multimodality Tests for Gene-Based Identification of Oncological Patients

    • Jose Ameijeiras-Alonso, Rosa M. Crujeiras
    Pages 45-61

  5. Hippocampus Shape Analysis via Skeletal Models and Kernel Smoothing

    • Eduardo García-Portugués, Andrea Meilán-Vila
    Pages 63-82

  6. Application of Quantile Regression Models for Biomedical Data

    • Mercedes Conde-Amboage, Ingrid Van Keilegom, Wenceslao González-Manteiga
    Pages 83-113

  7. Advances in Cytometry Gating Based on Statistical Distances and Dissimilarities

    • Hristo Inouzhe
    Pages 115-141

  8. Derivation of Optimal Experimental Design Methods for Applications in Cytogenetic Biodosimetry

    • Manuel Higueras, Jesús López-Fidalgo
    Pages 143-155

  9. Multiple Imputation for Compositional Data (MICoDa) Adjusting for Covariates

    • Abhisek Saha, Diane L. Putnick, Huang Lin, Edwina Yeung, Rajeshwari Sundaram, Shyamal Das Peddada
    Pages 157-184

  10. Integral Analysis of Circadian Rhythms

    • Jesús Vicente-Martínez, Pedro Francisco Almaida-Pagan, Antonio Martinez-Nicolas, Juan Antonio Madrid, Maria-Angeles Rol, María-Ángeles Bonmatí-Carrión
    Pages 185-236

  11. Modelling the Circadian Variation of Electrocardiographic Parameters with Frequency Modulated Models

    • Yolanda Larriba, Cristina Rueda
    Pages 237-253

  12. Novel Modeling Proposals for the Analysis of Pattern Electroretinogram Signals

    • Christian Canedo, Itziar Fernández, Rosa M. Coco, Rubén Cuadrado, Cristina Rueda
    Pages 255-273

  13. Back Matter

    Pages 275-276
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Editors and Affiliations

  • Department of Statistics and Operations Research, University of Valladolid, Valladolid, Spain

    Yolanda Larriba

About the editor

Yolanda Larriba is an Assistant Professor at the Department of Statistics and Operations Research of the University of Valladolid (Spain). Her research mainly concerns the development of statistical methodologies in the field of order restricted inference with applications to medical science.

Bibliographic Information

  • Book Title: Statistical Methods at the Forefront of Biomedical Advances

  • Editors: Yolanda Larriba

  • DOI: https://doi.org/10.1007/978-3-031-32729-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023

  • Hardcover ISBN: 978-3-031-32728-5Published: 10 August 2023

  • Softcover ISBN: 978-3-031-32731-5Due: 10 September 2023

  • eBook ISBN: 978-3-031-32729-2Published: 09 August 2023

  • Edition Number: 1

  • Number of Pages: XI, 276

  • Number of Illustrations: 14 b/w illustrations, 57 illustrations in colour

  • Topics: Biostatistics, Biomedical Engineering and Bioengineering, Bioinformatics, Biological Techniques

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