Abstract
THE high content of arginine residues in protamines (salmine, for example, contains 85–88 per cent arginine1), the low molecular weight of these strongly basic proteins, and the accumulating data on the polymerization of N-carboxyl anhydrides of α-amino acids2, led us to a systematic study of the possibilities of synthesizing poly-arginine. In the present communication, we wish to report the preparation of poly-arginine by guanidization of poly-ornithine. The latter was synthesized in the manner previously described for its homologue, poly-lysine3.
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References
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KATCHALSKI, E., SPITNIK, P. Poly-arginine. Nature 164, 1092–1093 (1949). https://doi.org/10.1038/1641092a0
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DOI: https://doi.org/10.1038/1641092a0
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