Abstract
MUSCULAR exercise results in development of the muscles concerned, and it influences other parts of the body. A metabolic product of muscular activity is probably responsible for the muscle hypertrophy, and it is possible that such a hormone may circulate in the blood and stimulate other organs. To our knowledge the only experimental study of this question is that of Bělehrádek1, who fed tadpoles with artificially fatigued frog muscle. The weight of these tadpoles was increased by 28 per cent compared with controls fed on resting frog muscle, and they metamorphosed earlier than the controls. This has been confirmed by Siebert and Petow.2
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References
Arch. Int. Physiol., 22, 376; 1924.
Z. klin. Med., 102, 434; 1925.
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Fox, H., SMITH, G. A Growth-Stimulating Substance in Fatigued Muscle. Nature 130, 774 (1932). https://doi.org/10.1038/130774c0
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DOI: https://doi.org/10.1038/130774c0
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