Summary
Spherical, porous-polymer particles for column packing in high-performance liquid chromatography were prepared by suspension copolymerization of alkylvinyl ether with triethyleneglycol divinyl ether. The hydrophobicity of the packings was easily adjusted by changing the monomer ratio. The packings showed the usual reversed-phase liquid chromatographic properties, but did not sho abnormal retention, tailing and broadening of peaks and irreversible adsorption of ionic and aromatic substances, owing to the lack of ionic or aromatic groups. In addition, the packings were stable in alkaline solutions because of the relative alkali stability of C−O−C bonds as compared with CO−O and Si−O−C bonds in conventional packings.
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Hirayama, C., Ihara, H., Nagaoka, S. et al. Porous polymer packings from vinyl ether derivatives for reversed-phase liquid chromatography. Chromatographia 33, 19–24 (1992). https://doi.org/10.1007/BF02276845
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DOI: https://doi.org/10.1007/BF02276845