Abstract
The construction of PVC matrix type tripelennamine ion selective electrodes and their use for direct potentiometry, potentiometric titration and flow injection analysis of tripelennamine cation are described. The membranes of these electrodes consist of tripelennamine-tetraphenylborate, reineckate and picrylsulfonate ion-association complexes dispersed in PVC matrix with tributyl phosphate (TBP) plasticizer. The electrodes exhibit near-Nernstian response over the concentration range of 10−1-10−4 M tripelennamine over the pH range 4.5–8.0. Selectivity coefficients data obtained for 17 different organic and inorganic ions are presented. The results obtained for the determination of 29 μg/ml-29 mg/ml of tripelennamine with the proposed electrodes show average recoveries of 99.5–99.9% and mean standard deviations of 0.6–1.2%. The data agree well with those obtained by the standard methods.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
J. E. F. Reynolds,Martindale, The Extra Pharmacopoeia, The Pharmaceutical Press, London, 1982.
E. G. E. Clarke,Isolation and Identification of Drugs, Vol. 1, The Pharmaceutical Press, London, 1978.
H. C. Thompson, Jr., C. L. Holder, J. R. Althaus,Talanta 1983,30, 251.
L. G. Rushing, A. B. Gosnell, C. L. Holder, W. A. Korfmacher, W. Slikker,HRCCC, J. High Resol. Chromatogr. Commun. 1986,9, 435.
J. Krancmar, J. Blazck, Z. Stejskal,Pharmazie 1957,12, 803.
K. Selinger, R. Staroscik,Chem. Anal. (Warsaw) 1982,27, 223.
K. Fukamaki, N. Ishibashi,Bunseki Kagaku 1978,27, 152.
V. V. Cosofret,Membrane Electrodes in Drug Substances Analysis, Pergamon, Oxford, 1982, p. 169.
S. B. Bhise, C. V. S. Subrahmanyam, R. C. Srivastava,J. Pharm. 1983,17, 263.
S. S. M. Hassan, F. Elzawawy, S. A. Marzouk, E. M. Elnemma,Analyst 1992,117, 1683.
G. J. Moody, J. D. R. Thomas, in:Ion Selective Electrodes in Analytical Chemistry, (H. Freiser, ed.) Chapter 4, Plenum, London, 1978.
E. M. Elnemma, M. A. Hamada, S. S. M. Hassan,Talanta 1992,39, 1329.
G. J. Moody, J. D. R. Thomas,Ion-Selective Electrode Rev. 1979,1, 3.
IUPAC, Analytical Chemistry Division, Commission on Analytical Nomenclature,Pure Appl. Chem. 1976,48, 127.
G. J. Moody, R. B. Oke, J. D. R. Thomas,Analyst 1970,45, 910.
T. S. Ma, S. S. M. Hassan,Organic Analysis Using Ion Selective Electrodes, Vols. 1 and 2, Academic Press, London, 1982.
G. Gran,Analyst 1952,77, 661.
W. Selig,Microchem. J. 1977,22, 1.
The United States Pharmacopeia 1990, The United States Pharmacopeial Convention, Rockville, MD.
British Pharmacopoeia 1993, Vol. 1, Cambridge University Press, Cambridge.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
El Nemma, E.M. PVC membrane electrodes for potentiometric determination of tripelennamine. Mikrochim Acta 127, 259–263 (1997). https://doi.org/10.1007/BF01242732
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF01242732