Summary
An ultrastructural study of teeth with amelogenesis imperfecta revelaed various aspects of microcavities in the enamel surface, which ranged from isolated imprints of ameloblasts corresponding to the mildest lesions at the end of amelogenesis, to pits caused by the death of 20 to 30 ameloblasts at the beginning of amelogenesis. Abnormalities in the shape of the prisms can be observed. Further, crystals are distributed randomly within a prism or at the junction of 2 contiguous prisms while intercrystalline spaces are widened, indicating in various places the lack of a preferred orientation of the crystals. In amelogenesis imperfecta, two different crystalline periods are found: 1 of about 250 Å, the other of about 500 Å and over. The fact that amorphous areas are found among the crystals of enamel may be related to different stages of crystallization. However, it was not possible to find any lattice defect.
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References
Boyde, A.: The development of enamel structure. Proc. Royal Soc. Med.60, 923–928 (1967)
Boyde, A.: The surface of the enamel in human hypoplastic teeth. Archs Oral Biol.15, 897–898 (1970)
Hirai, G., Fearnhead, R.W.: Lattice defects in biological and synthetic apatites. Proc. of the 6th Conference on X-ray Optics and Microanalysis, pp. 863–872, Univ. of Tokyo Press 1972
Jongebloed, W.L., Molenaar, I., Arends, J.: Morphology and size-distribution of sound and acid-treated enamel crystallites. Calcif. Tiss. Res.19, 109–123 (1975)
Kerebel, B., Daculsi, G.: Amelogenesis Imperfecta; étude structurale, ultrastructurale et cristallographique. J. Biol. Buc.4, 43–60 (1976a)
Kerebel, B., Daculsi, G.: Ultrastructural and cristallographic study of some biological apatites. 54th general session International Association for Dental Research, Marburg, Germ. Fed. Rep., March 12 and 13, 1976b
Kerebel, B., Ribay, B.: Amélogénèse imparfaite; étude au microscope photonique et au microscope électronique à balayage. Actualités Odonto-Stomatologiques93, 37–56 (1971)
Langdon, D., Dykes, E., Fearnhead, R.W.: Defects, diffusion and dissolution in biological and synthetic apatite. Colloques internationaux CNRS 230, Physicochimie et cristallographie des apatites d'intérêt biologique, 381–388 (1973)
Poole, D.F.G., Silverstone, L.M.: Observations with the scanning electron microscope on trauma-induced microcavities in human enamel. Agents Oral Biol14, 1323–1329 (1969)
Sauk, J.J., Cotton, W.R., Lyon, H.W., Witkop, C.J., Jr.: Electron optic analysis of hypomineralized Amelogenesis Imperfecta in man. Archs. oral Biol.17, 771–779 (1972a)
Sauk, J.J., Lyon, H.W., Witkop, C.J., Jr.: Electron optic microanalysis of two gene products in enamel of female heterozygous for X-linked hypomaturation Amelogenesis Imperfecta. Amer. J. Hum. Gen.24, 267–276 (1972b)
Shafer, W.G., Hine, M.K., Levy, B.M.: A textbook of oral pathology. Philadelphia: Saunders, 1974
Vahl, J.: Gesunder und pathologish veränderter Zahnschmelz. Eine mikromorphologische und biokristallographische Strukturanalyse. (Sammlung Meusser) Leipzig: J. Ambrosius Barth 1971
Witkop, C.J., Rao, S.: Inherited defects in tooth structure. In: Bergsma, D., Birth defects, original article series. Part XI, Orofacial Structures, vol. 7, 153–184. New York: Williams and Wilkins Co. 1971
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Kerebel, B., Daculsi, G. Ultrastructural study of amelogenesis imperfecta. Calc. Tis Res. 24, 191–197 (1977). https://doi.org/10.1007/BF02223315
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DOI: https://doi.org/10.1007/BF02223315