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The human neutrophilic promyelocyte

A correlated phase and electron microscopic study

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Summary

The developmental changes in the neutrophilic promyelocytes from normal human bone marrow have been analyzed by means of phase contrast and electron microscopy. This developmental phase is characterized by the elaboration of primary (azurophillysosomal) granules and the entire intracellular machinery is directed principally toward this goal. The promyelocyte stage has been subdivided into three arbitrary stages based upon morphological, histochemical and functional characteristics which relate to the onset, active production and cessation of primary granulogenesis.

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Authors and Affiliations

  1. Department of Anatomy, The Ohio State University, Columbus, Ohio, USA

    G. Adolph Ackerman

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  1. G. Adolph Ackerman
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Additional information

Supported by Grant No. AM-HE-12084-12 from the National Institutes of Health, Bethesda, Maryland.

Appreciation is expressed to Dr. Arthur Sagone who performed the bone marrow aspirations and to Marjorie Griffith, Anita Topson and Barbara Jordan for their technical assistance.

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Adolph Ackerman, G. The human neutrophilic promyelocyte. Z. Zellforsch. 118, 467–481 (1971). https://doi.org/10.1007/BF00324614

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  • DOI: https://doi.org/10.1007/BF00324614

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