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Zur formalen Genetik der Adenylatkinasen (EC: 2.7.4.3) Hinweis auf Kopplung der loci für AK und ABO

Formal genetics of the adenylatekinase polymorphism; Evidence for linkage between the loci for AK and ABO

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Summary

The polymorphism of adenylate kinase has been investigated in a series of 220 families with 530 children from southwestern Germany. The segregation of the children's phenotypes is in agreement with the formal two-allele-model. —The analysis of linkage for the loci ABO and AK confirms the analysis of Rapley et al.; the distance between the loci seems to be not smaller than 0.1, not greater than 0.2.

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Literatur

  • Bowman, J. E., H. Frischer, F. Ajmar, P. E. Carson, and M. K. Gower: Population, family, and biochemical investigation of human adenylate kinase polymorphism. Nature (Lond.) 214, 1156 (1967).

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  • Fildes, R. A., and H. Harris: Genetically determined variation of adenylate kinase in man. Nature (Lond.) 209, 261 (1966).

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  • Maynard-Smith, S., L. S. Penrose, and C. A. B. Smith: Mathematical Tables for Research Workers in Human Genetics. London: Churchill 1961.

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  • Rapley, S., E. B. Robson, H. Harris, and S. Maynard-Smith: Data on the incidence, segregation and linkage relations of the adenylate kinase (AK) polymorphism. Ann. hum. Genet. 31, 237 (1968).

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Authors and Affiliations

  1. Institut für Humangenetik und Anthropologie der Universität Freiburg i. Br., Freiburg i. Br., Deutschland

    B. Wille & H. Ritter

  2. Institut für Humangenetik und Anthropologie der Universität, Schloß, 7400, Tübingen

    H. Ritter

Authors
  1. B. Wille
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  2. H. Ritter
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Mit Unterstützung durch die Deutsche Forschungsgemeinschaft.

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Wille, B., Ritter, H. Zur formalen Genetik der Adenylatkinasen (EC: 2.7.4.3) Hinweis auf Kopplung der loci für AK und ABO. Hum Genet 7, 263–264 (1969). https://doi.org/10.1007/BF00273180

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  • DOI: https://doi.org/10.1007/BF00273180

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