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Separation of vinca alkaloids by GLC

Trennung von Vinca-Alkaloiden durch Gas-Chromatographie

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Zusammenfassung

Mit Hilfe von OV-101 als stationä-rer Phase und einem Temperaturprogramm (200–300° C, 5° C/min) konnten nahe verwandte Vinca-Alkaloide (Stereo- und Strukturisomere, Esterhomologe von Vincamin- und Apovincaminsäure) gas-chromatographisch getrennt werden.

Summary

A new GLC method was developed for the separation of vinca alkaloids. OV-101 stationary phase and programmed temperature analysis were used for the investigations. By this method the separation of closely related vinca alkaloids can be performed such as stereo and structural isomers, ester homologues of vincaminic and apovincaminic acids.

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Authors and Affiliations

  1. Chemical Works of Gedeon Richter Ltd., P.O.B. 27, H-1475, Budapest 10, Hungary

    M. Gazdag, K. Mihályfi & G. Szepesi

Authors
  1. M. Gazdag
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  2. K. Mihályfi
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  3. G. Szepesi
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Gazdag, M., Mihályfi, K. & Szepesi, G. Separation of vinca alkaloids by GLC. Z. Anal. Chem. 309, 105–108 (1981). https://doi.org/10.1007/BF00496115

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  • DOI: https://doi.org/10.1007/BF00496115

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