Skip to main content
SpringerLink
Log in

Effect of visual deprivation on composition of structural proteins of the rabbit central visual system

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The composition of membrane proteins of the visual cortex and superior colliculus of normal and visually deprived (for 2.5 months after birth) rabbits was studied by disk electrophoresis in polyacrylamide gel. Membrane proteins were extracted consecutively with 1% solution of Triton X-100 and 0.1% solution of sodium dodecylsulfate. One fraction, consisting of high-molecular-weight proteins, was not found in the membrane proteins of the central visual system of the light-deprived rabbits, and the relative percentage of proteins in the various fractions also differed from normal. It can be concluded from these results that visual deprivation gives rise to considerable quantitative and qualitative changes in the composition of the brain membrane proteins, with some specificity toward the central visual structures.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. A. A. Volokhov and N. N. Shilyagina, Zh. Vyssh. Nerv. Deyat., No. 4, 735 (1972).

    Google Scholar 

  2. L. M. Gershtein, Tsitologiya, No. 4, 437 (1975).

    Google Scholar 

  3. Z. D. Pigareva, Usp. Sovr. Biol.,79, No. 1, 48 (1975).

    Google Scholar 

  4. M. G. Uzbekov and T. M. Ivanova, Byull. Éksp. Biol. Med., No. 12, 31 (1974).

    Google Scholar 

  5. M. G. Uzbekov, V. P. Polyakov, and T. M. Ivanova, Lab. Delo, No. 2, 120 (1976).

    Google Scholar 

  6. M. G. Uzbekov and Z. D. Pigareva, in: The Physiology and Biochemistry of Mediator Processes. Proceedings of an All-Union Conference [in Russian], Moscow (1976), p. 75.

  7. P. Grobstein, K. L. Chow, and P. C. Fox, Proc. Nat. Acad. Sci. USA,72, 1543 (1975).

    Google Scholar 

  8. O. H. Lowry, N. J. Rosebrough, A. L. Farr, et al., J. Biol. Chem.,193, 165 (1951).

    Google Scholar 

  9. K. Mitros, M. Kossut, and M. Slosarska, in: Symposium on the Visual System. Abstracts, Reinhardsbrunn (1975), p. 21.

  10. K. Richardson and S. P. R. Rose, J. Neurochem.,21, 531 (1973).

    Google Scholar 

  11. S. P. R. Rose, Brain Res.,38, 171 (1972).

    Google Scholar 

  12. S. P. R. Rose and A. K. Sinha, Life Sci.,15, 223 (1974).

    Google Scholar 

Download references

Authors
  1. M. G. Uzbekov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. M. Ivanova
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Uzbekov, M.G., Ivanova, T.M. Effect of visual deprivation on composition of structural proteins of the rabbit central visual system. Bull Exp Biol Med 82, 1507–1509 (1976). https://doi.org/10.1007/BF00799793

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00799793

Key Words

Search

Navigation