Abstract
A study of the effects of synthetic analogs of dermorphin which are prime agonists of the μ-opiate receptors, on cell division in the corneal and lingual epithelium of albino rats showed that both analogs depressed DNA synthesis in the corneal and lingual epithelium 4 h after administration. In the lingual epithelium DNA synthesis and the mitogenic index were still depressed 24 h after drug administration. In the cornea cell division parameters had normalized by this time.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 11, pp. 508–510, November, 1994
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Fleishman, M.Y., Radivoz, M.I., Timoshin, S.S. et al. Effect of synthetic analogs of dermorphin on mitosis in the corneal and lingual epithelium of albino rats. Bull Exp Biol Med 118, 1205–1207 (1994). https://doi.org/10.1007/BF02444626
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DOI: https://doi.org/10.1007/BF02444626