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Epidermal growth factor receptor: its role in Drosophila eye differentiation and cell survival

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Abstract

The Drosophila epidermal growth factor receptor (EGFR), functioning through the Ras/Raf/MAPK pathway, promotes cell proliferation and differentiation. Recent work has demonstrated that EGFR functions via the same Ras/Raf/MAPK pathway to promote cell survival. This review summarizes the role of EGFR in differentiation and survival during Drosophila eye development.

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Authors and Affiliations

  1. Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, 02129

    P. Kurada & K. White

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  1. P. Kurada
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  2. K. White
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Kurada, P., White, K. Epidermal growth factor receptor: its role in Drosophila eye differentiation and cell survival. Apoptosis 4, 239–243 (1999). https://doi.org/10.1023/A:1009648724937

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