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The effect of homogenization temperature upon the apparent cellular compartmentalization of unoccupied estrogen receptor

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Summary

Homogenization of rat uterus at elevated temperatures results in an increased nuclear localization of unoccupied estrogen receptor. This is a nonlinear effect which is accounted for by an increased population of KCl-resistant nuclear binding sites at the elevated homogenization temperatures.

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References

  1. Gorski, J., Toft, D., Shyamala, G., Smith, D., and Notides, A., Rec. Prog. Horm. Res.24 (1968) 45.

    CAS  PubMed  Google Scholar 

  2. Jensen, E. V., Suzuki, T., Kawashima, T., Stumpf, W. E., Jungblut, R., and DeSombre, E. R., Proc. natl Acad. Sci. USA59 (1968) 632.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Mueller, G. C., Vonderhaar, B., Kim, U. H., and Mahieu, M. L., Rec. Prog. Horm. Res.28 (1972) 1.

    CAS  PubMed  Google Scholar 

  4. Shyamala, G., and Gorski, J., J. biol. Chem.244 (1967) 1097.

    Article  Google Scholar 

  5. Anderson, J. N., Clark, J. H., and Peck, E. J. Jr, Biochem. biophys. Res. Commun.48 (1972) 1460.

    Article  CAS  PubMed  Google Scholar 

  6. Clark, J. H., Anderson, J. N., and Peck, E. J. Jr, Science176 (1972) 528.

    Article  CAS  PubMed  Google Scholar 

  7. Raam, S., Nemeth, E., Tamura, H., O'Brian, D. S., and Cohen, J. L., Eur. J. Cancer clin. Oncol.18 (1982) 179.

    Article  Google Scholar 

  8. Raam, S., Richardson, G. S., Bradley, F., Maclaughlin, D., Sun, L., Frankel, F., and Cohen, J. L., Breast Cancer Res. Treat.3 (1982) 179.

    Article  Google Scholar 

  9. Robertson, N. M., Kusnik, W. F., Grove, B., Miller-Diener, A., Webb, M. L., and Litwack, G., Endocr. Soc. Prog. Abstr. 67th Ann. Meet. (1985) 20.

  10. Moncharmont, B., and Parikh, I., Biochem. biophys. Res. Commun.114 (1984) 107.

    Article  Google Scholar 

  11. Gasc, J.-M., Renoir, J.-M., Radanyi, C., Joab, I., and Balieu, E.-E., C. R. Acad. Sci., Paris295 (1984) 707.

    Google Scholar 

  12. Gasc, J.-M., Renoir, J.-M., Radanyl, C., Joab, I., Tuohimaa, P., and Balieu, E.-E., J. Cell Biol.99 (1984) 1193.

    Article  CAS  PubMed  Google Scholar 

  13. King, W. J., and Greene, G. L., Nature (Lond.)307 (1984) 745.

    Article  CAS  PubMed  Google Scholar 

  14. McClellan, M., West, N., Tacha, D. Greene, G., and Brenner, R., Endocrinology114 (1984) 2002.

    Article  CAS  PubMed  Google Scholar 

  15. Perrot-Applanat, M., Logeat, F., Groyer-Picard M. T., and Milgrom, E., Endocrinology116 (1985) 1473.

    Article  CAS  PubMed  Google Scholar 

  16. Welshons, W. V., Lieberman, M. E., and Gorski, J., Nature (Lond.)307 (1984) 747.

    Article  CAS  PubMed  Google Scholar 

  17. Welshons, W. V., Krummel, B. M., and Gorski, J., Endocrinology117 (1985) 2140.

    Article  CAS  PubMed  Google Scholar 

  18. Gravanis, A., and Gurpide, E., J. Steroid Biochem.24 (1986) 469.

    Article  CAS  PubMed  Google Scholar 

  19. Callard, G. V., and Mak, P., Proc. natl Acad. Sci. USA82 (1984) 1336.

    Article  Google Scholar 

  20. Sheridan, P. J., Buchanan, J. M., Anselmo, V. C., and Martin, P. M., Nature (Lond.)282 (1979) 579.

    Article  CAS  PubMed  Google Scholar 

  21. Martin, P. M., and Sheridan, P. J., J. Steroid Biochem.16 (1982) 215.

    Article  CAS  PubMed  Google Scholar 

  22. Korenman, S. G., J. clin. Endocr.28 (1968) 127.

    Article  CAS  PubMed  Google Scholar 

  23. Clark, J. H., and Peck, E. J., Jr, Nature (Lond.)260 (1976) 635.

    Article  CAS  PubMed  Google Scholar 

  24. Bulger, W. H., Okulicz, W. C., and Kupfer, D., J. Steroid Biochem.24 (1986) 795.

    Article  CAS  PubMed  Google Scholar 

  25. Raam, S., Steroids47 (1985) 337.

    Article  Google Scholar 

  26. Szego, C. M., and Pietras, R. J., Nature (Lond.)317 (1985) 38.

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Biological Sciences, The University of Alabama in Huntsville, 35899, Huntsville, Alabama, USA

    P. S. Campbell & K. A. Swanson

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  1. P. S. Campbell
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  2. K. A. Swanson
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This work was supported by NSF Research Grant PCM-8409586.

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Campbell, P.S., Swanson, K.A. The effect of homogenization temperature upon the apparent cellular compartmentalization of unoccupied estrogen receptor. Experientia 45, 171–173 (1989). https://doi.org/10.1007/BF01954864

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  • DOI: https://doi.org/10.1007/BF01954864

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