Skip to main content
SpringerLink
Log in

Immunomodulating effects in vitro of a hydroxythiazolobenzimidazole in the absence of mitogenicity

  • Specialia
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Wy-13, 876, a hydroxythiazolobenzimidazole, enhanced in vitro antibody formation by mouse spleen cells immunized with sheep red blood cells. The optimal dose was 25–50 μg/culture. The compound did not have a mitogenic effect at any dose.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. J. Watson, E. Trenkner and M. Cohn, J. exp. Med.138, 699 (1973).

    Article  PubMed  Google Scholar 

  2. J. Andersson, J. Melchers, C. Galanos and O. Ludevitz, J. exp. Med.39, 943 (1973).

    Article  Google Scholar 

  3. A. Coutinho and G. Möller, Scand. J. Immun.3, 133 (1974).

    Google Scholar 

  4. G. H. Warren, L. Mills and H. Friedman, J. reticuloendoth. Soc.20, 64A (1976).

    Google Scholar 

  5. R. L. Fenichel, F. J. Gregory and H. E. Alburn, Br. J. Cancer33, 329 (1976).

    PubMed  Google Scholar 

  6. R. L. Fenichel, H. E. Album, W. E. Tucker, G. H. Warren and F. J. Gregory, Proc. 66th Meeting Am. Ass. Cancer Res., San Diego, California, May 1975.

  7. I. Kamo, C. Patel, J. Kateley and H. Friedman, J. Immun.114, 1749 (1975).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Microbiology, Wyeth Laboratories, Inc., P.O. Box 8299, 19101, Philadelphia, (Pennsylvania), (USA)

    G. H. Warren, L. Mills & H. Friedman

  2. Albert Einstein Medical Center, 19141, Philadelphia, (Pennsylvania), (USA)

    G. H. Warren, L. Mills & H. Friedman

Authors
  1. G. H. Warren
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Mills
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Friedman
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Warren, G.H., Mills, L. & Friedman, H. Immunomodulating effects in vitro of a hydroxythiazolobenzimidazole in the absence of mitogenicity. Experientia 34, 802–803 (1978). https://doi.org/10.1007/BF01947337

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01947337

Keywords

Search

Navigation