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The effect of renal hydrodynamics on immune complex deposition

  • Specialia
  • Haematologica, Immunologica
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Summary

The role of renal hydrodynamics on renal deposition of immune complexes was evaluated in acute serum sickness. Using i.v. radiolabelled antigen in rabbits under a variety of hydrodynamic alterations, these studies suggested that although intrarenal hydrodynamics influence renal deposition of immune complexes factors other than intrarenal hydrostatic pressure may be important.

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Author information

Authors and Affiliations

  1. Department of Medicine, Nephrology and Clinical Immunology, Department of Pediatrics and Surgery, University of Colorado Medical Center, 4200 East Ninth Avenue, Box C 233, 80220, Denver, Colorado, USA

    T. Ozawa, R. Weil III & R. M. McIntosh

Authors
  1. T. Ozawa
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  2. R. Weil III
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  3. R. M. McIntosh
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Additional information

Supported by grants in aid from the Rocky Mountain Kidney Foundation, Colorado Heart Association, USPHS No. GRS 5 SO1 RR 05357 and USPHS No. HD 04024.

Dr. Ozawa is a fellow in Neprhology.

This work was performed during the tenure of an Established Investigatorship from the American Heart Association (Dr.McIntosh).

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Ozawa, T., Weil, R. & McIntosh, R.M. The effect of renal hydrodynamics on immune complex deposition. Experientia 32, 933–934 (1976). https://doi.org/10.1007/BF02003776

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  • DOI: https://doi.org/10.1007/BF02003776

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