Sur le rôle possible des deux acides nucléiques dans la cellule vivante

Summary

According to the writer's theory a great number of different desoxyribonucleic and ribonucleic acids exist in each cell: desoxyribonucleic acids in the nucleus (genes) and ribonucleic acids in the cytoplasm (microsomes). Through catalytic actions the macromolecular desoxyribonucleic acids govern the building of macromolecular ribonucleic acids, and, in turn, these control the production of cytoplasmic enzymes. In truth, the enzymic equipment results simultaneously from the effect of ribonucleic acids (catalytic action) and from the effect of substrates (mass action). This hypothesis explains cellular differentiation (multicellular organism) through constitutional variations of cytoplasmic ribonucleic acids. The writer's fundamental arguments come from the study of bacterial biology, especially from the study of mutations directed by principles of desoxyribonucleic nature.