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Ein Sensibilisator der therapeutischen Digitaliswirkung

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Summary

Complexes of bivalent tin with polyoxybenzene-polysulfonic acids have a diuretic effect, when injected subcutaneously in dogs or rabbits. The same compounds also sensibilize the cardiotonic effect of digitalis-substances on the isolated heart or on fragments of the isolated heart as usually employed for testing digitalis-substances.

In a small number of patients suffering from heart disease, a rapid increase of their till then lowered diuresis was induced through subcutaneous injections of a solution of the above mentioned tin complex.

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References

  1. Ein Verfahren zur Reindarstellung dieser Stoffe wurde zum Patent angemeldet (H. Handovsky undE. de Mahler, Brüssel, Nr. 359270 vom 16, 2. 1946).

  2. Vgl.Handovsky, Arch. exp. Path. u. Pharm.114, 39 (1926).

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Authors and Affiliations

  1. Laboratorium der Universitätsfrauenklinik Gent (Belgien), Belgium

    Hans Handovsky

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  1. Hans Handovsky
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Handovsky, H. Ein Sensibilisator der therapeutischen Digitaliswirkung. Experientia 2, 317–318 (1946). https://doi.org/10.1007/BF02157059

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  • DOI: https://doi.org/10.1007/BF02157059

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