Abstract
IN an earlier1 communication the occurrence of an adrenaline-like pressor substance in ether extracts of various animal organs has been reported. The primary extracts were made with two volumes of alcohol. After evaporation of the alcohol from the filtrate and removal of fats and lipoids with ether, the clear aqueous phase was subjected to dialysis for forty-eight hours in 'Cellophane' bags against running water. The content in the bags after dialysis showed a strong pressor action on the cat in chloralose anæsthesia. On concentration and treatment with six volumes of alcohol, the pressor activity was found partly in the precipitate and partly in the filtrate. After this treatment the whole of the pressor activity became dialysable.
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Nature, 156, 18 (1945).
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EULER, U., ÖSTLUND, E. An Undialysable Pressor Principle in Organ Extracts. Nature 156, 49 (1945). https://doi.org/10.1038/156049b0
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DOI: https://doi.org/10.1038/156049b0
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