Abstract
Dodds and Lawson1 have stated that anol will induce œstrus in rats. W. Jadassohn, Uehlinger and Margot2 have investigated whether anol will cause enlargement of the nipples of guinea pigs by simple external application of the solution of this substance (nipple test with anol). The result was positive although not sostrong as with œstrone. Later, Dodds and Lawson3 found that pure anol in not very large doses failed to induce œstrus. We reinvestigated the action of pure anol in the nipple test and found it to be completely negative. (A solution of the same anol prepared a few months later showed a positive nipple test.)
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References
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FIERZ, H., JADASSOHN, W., UEHLINGER, E. et al. Action of Anol and its Derivatives on the Nipple of the Guinea Pig. Nature 141, 974 (1938). https://doi.org/10.1038/141974b0
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DOI: https://doi.org/10.1038/141974b0
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