Summary
The gas chromatographic analysis of amines after conversion to electron capture sensitive carbamates in two-phase systems has been studied. Hydrophilic compounds, for instance methylamine, are reacted with 2,2,2-trichloro-tert. butyl chloroformate. Quantitation below 10−7 M can be made by thermionic or electron capture detection. A hydrophobic amine, namely N,N-dimethyl-n-octylamine, was derivatized with 2,4,6-tribromophenyl chloroformate with addition of iodide ion to the aqueous phase. The favorable effect of iodide ion as well as the choice of pH and chloroformate ester is discussed.
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Ahnfelt, N.O., Hartvig, P. & Karlsson, K.E. Derivatization of amines with chloroformate esters for gas chromatographic analysis. Chromatographia 16, 60–62 (1982). https://doi.org/10.1007/BF02258870
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DOI: https://doi.org/10.1007/BF02258870