Summary
The relative intestinal absorption of heme- and non heme-iron in connection with a standardized test meal was studied in a group of fertile women given 16 mg Fe in the form of FeSO4 and 2 mg Fe in the form of hemoglobin. Both in normal subjects and in women with iron deficiency, the heme-iron was significantly better absorbed (16.13%±S.D. 8.0 vs 4.59±3.4, p<0.01 and 22.03±8.9 vs 9.45±7.8, p<0.05). For targeted prophylaxis of iron deficiency with small, side-effect-free doses, heme-iron is thus a valuable component which increases the absorption by about 40%. Heme-iron does not cause high concentrations in the intestinal lumen of free radical inducing, possibly harmful ferric iron.
Zusammenfassung
Die relative intestinale Resorption von Haem- und Nichthaem-Eisen in Verbindung mit einer standardisierten Testmahlzeit wurde bei fertilen Frauen sowohl bei normalen Versuchspersonen als auch bei Frauen im Eisenmangel gemessen. Im Eisenmangel wurde das Haem-Eisen deutlich besser resorbiert (16.13%±S.D. 8.0 gegenüber 4.59±3.4, p<0.01, sowie 22.03±8.9 gegenüber 9.45±7.8, p<0.05). Für die gezielte Prophylaxe eines Eisenmangels mit kleinen, nebeneffektfreien Dosierungen ist Haem-Eisen daher eine wertvolle Komponente, welche die Resorption um 40% steigert. Haem-Eisen verursacht keine hohen Konzentrationen freier Radikale im intestinalen Lumen, die möglicherweise schädlich wirkendes zweiwertiges Eisen induziert.
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Ekman, M., Reizenstein, P. Comparative absorption of ferrous and heme-iron with meals in normal and iron deficient subjects. Z Ernährungswiss 32, 67–70 (1993). https://doi.org/10.1007/BF01610086
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DOI: https://doi.org/10.1007/BF01610086