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Quantitative comparison of dipole models for steady-state currents in excitable membranes

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Abstract

The dipole models for steady-state currents in excitable membranes of Arndt, Bond and Roper and of Hamel and Zimmerman are compared by fitting the equations to the data of Gilbert and Ehrenstein. The more complex Hammel and Zimmerman model does not fit the data as well as does the simpler Arndt, Bond and Reper model. When fitting the data, the Hammel and Zimmerman current equation reduces to the Arndt, Bond and Roper current equation because of the values assumed by the parameters. An interpretation is given for the parameter values obtained with the Arndt, Bond and Roper model.

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Arndt, R.A., Roper, L.D. Quantitative comparison of dipole models for steady-state currents in excitable membranes. Bulletin of Mathematical Biophysics 34, 305–324 (1972). https://doi.org/10.1007/BF02476444

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