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Bone mineral and body fat measurements by two absorptiometry systems: Comparisons with neutron activation analysis

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Abstract

In 185 adults (68 white and 31 black males, 66 white and 20 black females), total body bone mineral density and content and body fat% were measured by two dual energy X-ray absorptiometry (DXA) systems—Norland XR-26, software version 2.4, and Lunar DPX, software versions 3.4 and 3.6. In a subgroup of 18 males (10 white, 8 black), body fat% and total body calcium were also measured by in vivo neutron activation analysis (IVNA). For total body calcium, the DPX 3.4 system gave the highest (1239 g), IVNA the lowest (1195 g), and the XR-26 (1226 g) was not significantly different from the DPX 3.6 results. For fat%, the XR-26 system gave the highest estimate (23.5%), whereas measurements by the DPX 3.4 and 3.6 systems (17.4 and 18.2%) were similar to the IVNA measurements (18.3%). BMD and BMC measurements by the two DXA systems were highly correlated but significantly different for the entire studied population except in the case of BMC in black males.

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References

  1. Cameron JR, Sorenson JA (1963) Measurement of bone mineral in vivo: an improved method. Science 142:230–232

    Google Scholar 

  2. Mazess RB, Ort M, Judy P (1970) Absorptiometric bone mineral determination using 153 Gd. In: Cameron JR (ed) Proc Bone Measurement Conf. CONF-700515. U.S. Atomic Energy Commission, pp 308–312

  3. Roos B, Rosengren B, Skoldborn H (1970) Determination of bone mineral content in lumbar vertebrae by a double gamma-ray technique. In: Cameron JR (ed) Proc Bone Measurement Conf CONF-700515. U.S. Atomic Energy Commission, pp 243–253

  4. Mazess RP, Peppler W, Chesnut CH III, Nelp WB, Cohn SH, Zanzi I (1981) Total body bone mineral and lean body mass by dual-photon absorptiometry—II. Comparison with total body calcium by neutron activation analysis. Calcif Tissue Int 33:361–363

    Google Scholar 

  5. Slosman DO, Rizzoli R, Buchs B, Piana F, Donath A, Bonjour J-P (1990) Comparative study of the performances of x-ray and gadolinium 153 bone densitometers at the level of the spine, femoral neck and femoral shaft. Eur J Nuc Med 17:3–9

    Google Scholar 

  6. Borders J, Kerr E, Sartoris DJ, Stein JA, Ramos E, Moscona AA, Resnick D (1989) Quantitative dual-energy radiographic absorptiometry of the lumbar spine: in vivo comparison with dual-photon absorptiometry. Radiology 170:129–131

    Google Scholar 

  7. Wahner HW, Dunn WL, Brown ML, Morin RL, Riggs BL (1988) Comparison of dual-energy x-ray absorptiometry and dual photon absorptiometry for bone mineral measurements of the lumbar spine. Mayo Clin Proc 63:1075–1084

    Google Scholar 

  8. Arai H, Ito K, Nagao K, Furutachi M (1990) The evaluation of three different bone densitometry systems: XR-26, QDR-1000, and DPX. Image Tech Infor Display 22:1–6

    Google Scholar 

  9. Goodsitt MM (1992) Evaluation of a new set of calibration standards for the measurement of fat content via DPA and DXA. Med Phys 19:35–44

    Google Scholar 

  10. Roubenoff R, Kehayias JJ, Dawson-Hughes B, Heymsfield SB (1993) Use of dual-energy x-ray absorptiometry in body composition studies: not yet a “gold standard”. Am J Clin Nutr 58:589–591

    Google Scholar 

  11. Cohn SH (1981) In vivo neutron activation analysis: state of the art and future prospects. Med Phys 8:145–154

    Google Scholar 

  12. Stamatelatos IE, Dilmanian FA, Ma R, Lidofsky JL, Weber DA, Pierson RN Jr, Kamen Y, Yasumura S (1993) Calibration for measuring total body nitrogen with a newly upgraded prompt gamma neutron activation facility. Phys Med Biol 38:615–626

    Google Scholar 

  13. Cohn SH, Vaswani AN, Yasamura S, Yuen K, Ellis KJ (1984) Improved models for determination of body fat by in vivo neutron activation. Am J Clin Nutr 40:255–259

    Google Scholar 

  14. Nord RH (1992) Work in progress: a cross-correlation study on four DXA instruments designed to culminate in intermanufacturer standardization. Osteoporosis Int 2:210–211

    Google Scholar 

  15. Mazess B, Collick B, Trempe J (1989) Performance evaluation of a dual-energy x-ray bone densitometer. Calc Tissue Int 44:228–232

    Google Scholar 

  16. Sullivan JC, Clark RR, Kuta JM (1992) Comparison of hydrostatic weighing, dual energy X-ray absorptiometry, and skinfold predictions in adult females. Med Sci Sports Exerc 24:358

    Google Scholar 

  17. Mazess RB, Peppler WW, Gibbons M (1984) Total body composition by dual-photon (153Gd) absorptiometry. Am J Clin Nutr 40:834–839

    Google Scholar 

  18. Wang J, Dilmanian FA, Thornton J, Russell M, Burastero S, Mazariegos M, Heymsfield SB, Pierson RN Jr (1993) In: Ellis KJ, Eastman JD (eds) Human body composition Plenum Press, New York, pp 31–34

    Google Scholar 

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Pierson, R.N., Wang, J., Thornton, J.C. et al. Bone mineral and body fat measurements by two absorptiometry systems: Comparisons with neutron activation analysis. Calcif Tissue Int 56, 93–98 (1995). https://doi.org/10.1007/BF00296337

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  • DOI: https://doi.org/10.1007/BF00296337

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