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Intermolekulare Wechselwirkung zwischen Glyzerin und Katalase. Einfluß auf die Strahlenempfindlichkeit des Enzyms

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Zusammenfassung

Die Inaktivierung von Katalase durch Röntgenstrahlen in Gegenwart von Glyzerin wurde untersucht. Sehr geringe Glyzerinmengen (0,0004 Vol.%) ergaben schon eine ausgezeichnete, maximale Schutzwirkung. Aus den Ergebnissen wird geschlossen, daß die Ursache für den Schutzeffekt eine Komplexbildung zwischen Glyzerin und Eisenzentren im Enzymmolekül ist.

Summary

The x-ray inactivation of catalase in the presence of glycerol was investigated. Even small amounts of glycerol (0.0004 vol.%) gabe an excellent and maximum protective effect. From the results it is concluded that complex formation between glycerol and iron centers in the enzyme molecule produces the protective effect.

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Authors and Affiliations

  1. Department of Physiology and Biophysics, University of Arkansas School of Medicine, and Radioisotope Service, VA Hospital, Little Rock, Arkansas

    W. Lohmann, A. J. Moss, W. H. Perkins & Ch. F. Fowler

Authors
  1. W. Lohmann
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  2. A. J. Moss
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  3. W. H. Perkins
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  4. Ch. F. Fowler
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Additional information

Herrn Prof. Dr. B.Rajewsky zum 70. Geburtstag gewidmet.

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Lohmann, W., Moss, A.J., Perkins, W.H. et al. Intermolekulare Wechselwirkung zwischen Glyzerin und Katalase. Einfluß auf die Strahlenempfindlichkeit des Enzyms. Biophysik 2, 16–21 (1964). https://doi.org/10.1007/BF01189272

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  • DOI: https://doi.org/10.1007/BF01189272

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