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Evaluation of the gas transfer characteristics of porous copolyurethane oxygenator membranes

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Abstract

Porous copolyurethane membranes were prepared by solvent casting thin polymer films onto fibrous substrates. Pore size, water filtration rates, and gas transmission rates were measured to determine the influence of substrate, polymer type, and coating thickness on the membrane properties in the dry and wet state. Cellulosic substrates were not as satisfactory as were polyethylene, polyester, or nylon substrates. Porous membranes formed on these latter substrates had gas transfer rates similar to silicone rubber membranes. Although O2 transfer was similar to Gore-Tex® and Celgard®, CO2 transfer was less, apparently due to fewer pores in the copolyurethane membranes and possible wetting of the pores by water.

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References

  1. ASTM Standard test method for gas transmission rate of plastic film and sheeting.ANSI/ASTM D 1434-75, pp. 484–497.

  2. ASTM Standard method of test for density of plastics by the density gradient technique.ANSI/ASTM D1505-68, pp. 483–488.

  3. ASTM Standard method of test for pore size characteristics of membrane filters for use with aerospace fluids.ASTM F316-70, pp. 993–999.

  4. Baszkin, A. and D. J. Lyman. The interactions of plasma proteins with polymers. I. Relationship between polymer surface energy and protein adsorption/desorption.J. Biomed. Mater. Res. 16:393–403, 1980.

    Google Scholar 

  5. Chang, S.K., O.S. Hum, M.A. Moscarello, A.W. Neuman, W. Zinga, M.J. Leutheusser, and B. Ruegseffer. Platelet adhesion and solid surfaces.Med. Prog. Through Technology 5:57–66, 1977.

    CAS  Google Scholar 

  6. Damm, H.C..CRC The Practical Manual for Clinical Laboratory Procedures. Cleveland: Chemical Rubber Co., 1965, pp. 22–23.

    Google Scholar 

  7. Dorson, W.D. and M. Voorhees, Limiting models for the transfer of CO2 and O2 in membrane oxygenators.Trans. Am. Soc. Artif. Int. Organs 20:219–229, 1974.

    Google Scholar 

  8. Kelman, G.R. Digital computer procedure for the conversion of pCO2 into blood CO2 content.Respir. Physiol. 3:111–115, 1967.

    Article  CAS  PubMed  Google Scholar 

  9. Kelman, G.R. and J.F. Nunn. Nomograms for correction blood pO2, pCO2, pH and base excess for time and temperature.J. Appl. Physiol. 21:1484–1490, 1966.

    CAS  PubMed  Google Scholar 

  10. Kesting, R.E.Synthetic Polymeric Membranes. New York: McGraw-Hill, 1971, pp. 29–40.

    Google Scholar 

  11. Knight, P.M. and D.J. Lyman. Gas permeability of various block copolyether-urethanes.J. Membr. Science 17:245–254, 1984.

    CAS  Google Scholar 

  12. Lautier, A., P. Rey, J. Bizot, A. Faure, A. Sausse, and D. Laurent. Comparison of gaseous transfer through synthetic membranes for oxygenators.Trans. Am. Soc. Artif. Int. Organs 15:144–150, 1969.

    CAS  Google Scholar 

  13. Yasuda, H., and C.E. Lamaze. Transfer of gas to dissolved oxygen in water via porous and nonporous polymer membranes.J. Appl. Polym. Sci. 16:595–601, 1972.

    Article  CAS  Google Scholar 

  14. Zapol, W.M. and J. Ketteringham. Improved biomaterials for artificial lung membranes. InPolymers in Medicine and Surgery (Polymer Science and Technology Series) edited by R. L. Kronenthal, Z. Oser, and E. Martin. New York: Plenum Press, 1975, pp. 287–312.

    Google Scholar 

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Knight, P.M., Lyman, D.J. Evaluation of the gas transfer characteristics of porous copolyurethane oxygenator membranes. Ann Biomed Eng 13, 25–41 (1985). https://doi.org/10.1007/BF02371248

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