Summary
1. The reaction of sclareol and 13-episclareol with acetic anhydride has been studied. In addition to other products, manoyl oxide and 13-epimanoyl oxide are formed.
2. A mechanism for the dehydration of sclareol and 13-episclareol by acetic anhydride with the formation in each case of a mixture of manoyl oxide and 13-epimanoyl oxide has been proposed.
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References
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Khimiya Prirodnykh Soedinenii, Vol. 2, No. 3, pp. 176–179, 1966
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Vlad, P.F., Russo, A.G. & Lazur'evskii, G.V. Synthesis of manoyl oxide and 13-epimanoyl oxide. Chem Nat Compd 2, 139–141 (1966). https://doi.org/10.1007/BF01134233
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DOI: https://doi.org/10.1007/BF01134233