Summary
This paper describes a new computer-enhanced dual-channel SQUID susceptometer designed to achieve accuratein vivo estimates of tissue storage iron concentrations. We discuss the practical design considerations, instrumental noise performance and anticipated clinical resolution of the new system.
Riassunto
Questo lavoro descrive un nuovo suscettometro SQUID a doppio canale coadiuvato da computer destinato a raggiungere stime accuratein vivo delle concentrazioni di accumulo di ferro nei tessuti. Si discutono le considerazioni pratiche dello schema, la funzionalità sperimentale al rumore e la risoluzione clinica anticipata del nuovo sistema.
Similar content being viewed by others
References
J. W. Harris, D. E. Farrell andM. J. Messer:Clin. Res. A,26 504 (1978).
D. E. Farrell, J. H. Tripp, P. E. Zanzucchi, J. W. Harris, G. M. Brittenham andW. A. Muir:IEEE Trans. Magn., MAG-16, 818 (1980).
D. E. Farrell, J. H. Tripp, P. E. Zanzucchi, J. W. Harris, G. M. Brittenham andW. A. Muir:Biomagnetism, (Berlin, 1981), p. 507.
D. E. Farrell, J. H. Tripp, P. E. Zanzucchi, J. W. Harris, G. M. Brittenham, W. A. Muir andE. M. Bellon:Appl. Phys. Commun.,1, 1 (1981).
G. M. Brittenham, D. E. Farrell, J. W. Harris, E. S. Feldman, E. H. Danish, W. A. Muir, J. H. Tripp, J. N. Brennan andE. M. Bellon:N. Engl. J. Med.,307, 1671 (1982).
E. Weber:Electromagnetic Theory (New York, N. Y., 1965), p. 140.
C. M. Bastuscheck, D. Brenner, S. J. Williamson andL. Kaufman:Biomagnetism (Berlin, 1981), p. 519.
D. E. Farrell andP. Zanzucchi:Crit. Rev. Solid State Sci. (in press).
Author information
Authors and Affiliations
Additional information
Work supported by NIH grants HL24198 and AM25105.
Rights and permissions
About this article
Cite this article
Farrell, D.E., Tripp, J.H., Brittenham, G.M. et al. A clinical system for accurate assessment of tissue iron concentration. Il Nuovo Cimento D 2, 582–593 (1983). https://doi.org/10.1007/BF02455956
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02455956