Abstract
Various possibilities for the synthesis of N-hydroxy- and N-alkoxy derivatives of 2-aminobenzimidazoles — reductive cyclization of o-nitrophenylureas, the action of sodium amide on 1-alkoxybenzimidazoles, the ammonolysis of 1-alkoxy-2-iodobenzimidazoles, etc. — were investigated. Organometallic compounds of 1-alkoxybenzimidazoles were obtained for the first time, and their reactivities with respect to benzophenone, iodine, and 1-substituted benzimidazoles were studied. 2,2′-Dibenzimidazolyls that contain an alkoxy group in the 1 position were synthesized.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 200–206, February, 1979.
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Medvedeva, M.M., Pozharskii, A.F., Kuz'menko, V.V. et al. Behavior of N-alkoxybenzimidzoles with respect to nucleophilic reagents. Attempts to synthesize N-hydroxy-2-aminobenzimidazoles. Chem Heterocycl Compd 15, 166–172 (1979). https://doi.org/10.1007/BF00480362
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DOI: https://doi.org/10.1007/BF00480362