Abstract
We studied rapid changes in location of cyclic GMP inTetrahymena pyriformis. Insulin caused cGMP localization in cilia and near the plasma membrane (0.5–1 min). Later (1–5 min) cGMP localization was diffuse in cytoplasm with perinuclear accentuation. Inactive insulin analogs did not elicit these changes.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Csaba, G., Int. Rev. Cytol.95 (1985) 327.
Erecinska, M., Wilson, D. F., and Nishiki, K., Am. J. Physiol.234 (1978) C82.
Thompson, G. A. Jr, and Nozawa, Y., Biochim. biophys. Acta472 (1977) 55.
Kovacs, P., Csaba, G., Nagao, S., and Nozawa, Y., Microbios59 (1989) 123.
Garbers, D. L., J. biol. Chem.264 (1989) 9103.
Kovacs, P., and Csaba, G., Acta biol. hung.37 (1986) 205.
Csaba, G., and Sudar, F., Acta histochem. (Jena)77 (1985) 7.
Graves, M. G., Dickinson, J. R., and Swoboda, B. E., FEBS Lett.69 (1976) 165.
Dickinson, J. R., Graves, M. G., and Swoboda, B. E., FEBS Lett.65 (1976) 152.
Csaba, G., and Lantos, T., Experientia32 (1976) 321.
Gray, N. C., Dickinson, J. R., and Swoboda, B. E., FEBS Lett.81 (1977) 311.
Schultz, J. E., and Klumpp, S., Adv. cycl. Nucl. Prot. Phosphoryl. Res.17 (1984) 275.
Barsony, J., and Marx, S. J., Proc. natl. Acad. Sci. USA87 (1990) 1188.
Wescott, S. L., Nutman, T. B., Slater, J. E., and Kaliner, M. A., J. cycl. Nucl. Prot. Phosphoryl. Res.10 (1985) 189.
Culling, C. F. A., Allison, R. T., and Barr, W. T., Cellular Pathology Technique, 4th edn, p. 37. Butterworths, Boston 1985.
Somogyi, P., and Takagi, H., Neuroscience7 (1982) 1779.
Pearse, A. G. E., Histochemistry, Theoretical and Applied, 4th edn, p. 122. Churchill Livingstone, New York 1980.
Dougherty, W. J., in: Staining Procedures, 4th edn, pp. 27–38. Ed. G. Clark. Williams and Wilkins, Baltimore 1981.
Kramer, H., and Windrum, G. M., J. Histochem.3 (1955) 227.
Clark, G. (Ed.), in: Staining Procedures, 4th edn, pp. 171–216. Williams and Wilkins, Baltimore 1981.
Illiano, G., Tell, G. P., Siegel, M. I., and Cuatrecasas, P., Proc. natl Acad. Sci. USA70 (1973) 2443.
Fain, J. N., and Butcher, F. R., J. cycl. Nucl. Res.2 (1976) 71.
Pointer, R. H., Buther, F. R., and Fain, J. N., J. biol. Chem.251 (1976) 2987.
Brasitus, T. A., Field, M., Kimberg, D. V., Am. J. Physiol.231 (1976) 275.
Klumpp, S., Steiner, A. L., and Schultz, J. E., Eur. J. Cell Biol.32 (1983) 164.
Muto, Y., Kudo, S., Nagao, S., and Nozawa, Y., Exp. Cell Res.159 (1985) 267.
Katsuki, S., Arnold, W., Mittal, C., and Murad, F., J. cycl. Nucl. Res.3 (1977) 23.
Emami, S., and Perry, M. C., FEBS Lett.200 (1986) 51.
Kohidai, L., Darvas, Z., and Csaba, G., Acta microbiol. hung.34 (1987) 179.
Csaba, G., and Lantos, T., Acta protozool.13 (1975) 410.
Csaba, G., and Kohidai, L., Acta protozool.25 (1986) 331.
Csaba, G., and Kohidai, L., Acta protozool.28 (1989) 183.
Nilsson, J. R., and van Deurs, B., J. Cell Sci.63 (1983) 209.
Carpentier, J. L., Diabetologia32 (1989) 627.
Londos, C., Honner, R. C., and Dhillon, G. S., J. biol. Chem.260 (1985) 15139.
Fernandez-Almonacid, R., and Rosen, O. M., Molec. cell. Biol.7 (1987) 2718.
Kudo, S., Muto, Y., and Nozawa, Y., Comp. Biochem. Physiol.80 (1985) 813.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kohidai, L., Barsony, J., Roth, J. et al. Rapid effects of insulin on cyclic GMP location in an intact protozoan. Experientia 48, 476–481 (1992). https://doi.org/10.1007/BF01928167
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01928167