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The effect of continuously cooling the hypothalamic preoptic area on antibody titre in the rat

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  • Haematologica, Immunologica
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Summary

Continuous cooling of the hypothalamic preoptic area for 5 days, as well as sublethal infection withSalmonella enteritidis, increased the titre of antibodies against sheep erythrocytes, suggesting that the febrile response stimulates the humoral immune response.

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We thank Dr W. Mannheim from the Institute of Hygiene for kindly supplying the cultures ofS. enteritidis. This work was supported by the Schwerpunktprogramm Temperaturregulation und-adaptation of the Deutsche Forschungsgemeinschaft.

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Banet, M., Brandt, S. & Hensel, H. The effect of continuously cooling the hypothalamic preoptic area on antibody titre in the rat. Experientia 38, 965–966 (1982). https://doi.org/10.1007/BF01953680

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  • DOI: https://doi.org/10.1007/BF01953680

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