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Differences in in vitro incorporation of tritiated deoxycytidine and tritiated thymidine into human lymphocytes

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Summary

Human lymphocytes stimulated in vitro by PHA or PWM incorporate3H-CdR into DNA, but less well than3H-TdR. More3H-CdR is incorporated in populations enriched for T cells. No3H-CdR is used by cells stimulated by lipopolysaccharides under circumstances in which3H-TdR is incorporated. We conclude that human T cells and B cells differ in their ability to use3H-CdR.

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References

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Author notes

  1. T. L. Akasaka

    Present address: Department of Pediatrics, Saitama Medical College, Moroyama-machi, Iruma-gun, Saitama-ken, Japan

Authors and Affiliations

  1. Children's Hospital at Stanford, Department of Pediatrics, Stanford University School of Medicine, 94305, Stanford, California, USA

    T. L. Akasaka, Lynne Olds-Arroyo & J. J. Miller III

Authors
  1. T. L. Akasaka
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  2. Lynne Olds-Arroyo
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  3. J. J. Miller III
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Akasaka, T.L., Olds-Arroyo, L. & Miller, J.J. Differences in in vitro incorporation of tritiated deoxycytidine and tritiated thymidine into human lymphocytes. Experientia 35, 673–674 (1979). https://doi.org/10.1007/BF01960391

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  • DOI: https://doi.org/10.1007/BF01960391

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