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L-Azetidine-2-carboxylic acid, the antidermatophyte constituent of two marine sponges

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Summary

The aqueous ethanolic extract of 2 related marine spongesHaliclona sp. andChalinopsilla sp. displayed antidermatophyte activities specific forTrichophyton mentagrophytes. The active consituent of both sponges was isolated and shown to be L-azetidine-2-carboxylic acid.

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References

  1. RRIMP Museum Specimen, Numbers FN 1156Haliclona sp. and FN 0834Chalinopsilla sp. We thank I. G. Skinner for sponge taxonomy.

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Authors and Affiliations

  1. Microbiology Section and Chemistry Section, Roche Research Institute of Marine Pharmacology, P.O. Box 255, 2099, Dee Why, N.S.W., Australia

    B. Bach, R. P. Gregson, G. S. Holland, R. J. Quinn & J. L. Reichelt

Authors
  1. B. Bach
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  2. R. P. Gregson
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  3. G. S. Holland
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  4. R. J. Quinn
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  5. J. L. Reichelt
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Bach, B., Gregson, R.P., Holland, G.S. et al. L-Azetidine-2-carboxylic acid, the antidermatophyte constituent of two marine sponges. Experientia 34, 688 (1978). https://doi.org/10.1007/BF01947258

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