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The effect of intraluminal hydrostatic pressure on intestinal absorption in vivo

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Résumé

On a étudié I'influence de la pression hydrostatique intraluminale sur l'absorption d'eau, d'électrolytes et de glucose dans une anse perfusée d'iléon de chien in vivo. Une augmentation de la pression de 0 à 10 cm d'eau provoque une stimulation considérable de I'absorption isotonique. Un plateau est atteint à 20 cm d'eau, mais même après une perfusion à 30 cm d'eau, la muqueuse n'est pas lésée. Ces résultats suggèrent qu'il faut contrôler strictement les conditions de perfusion dans des expériences in vivo.

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Authors and Affiliations

  1. Départment de Chirurgie Expérimentale, Hôpital Cantonal Universitaire, CH-1011, Lausanne, Switzerland

    V. Mirkovitch, H. Menge & J. W. L. Robinson

Authors
  1. V. Mirkovitch
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  2. H. Menge
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  3. J. W. L. Robinson
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Additional information

Acknowledgments. This work was performed with the help of a grant from Zyma.S.A., Nyon. We are grateful to Mme H.Capt and MllesM. Augstburger, D. Mettraux andJ. Vouron for skilful technical assistance.

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Mirkovitch, V., Menge, H. & Robinson, J.W.L. The effect of intraluminal hydrostatic pressure on intestinal absorption in vivo. Experientia 30, 912–913 (1974). https://doi.org/10.1007/BF01938357

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  • DOI: https://doi.org/10.1007/BF01938357

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