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Chemical structure and biological activity ofp-disubstituted derivatives of benzene

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Zusammenfassung

Es wurden die i.v. LD50 einer Gruppep-disubstituierter Benzolderivate, welche alle Kombinationen der erwähnten Substituenten enthielten, in Polyvinylpyrrolidonlösungen bestimmt. Der Zusammenhang zwischen der chemischen Struktur dieser Verbindungsklasse und ihrer biologischen Aktivität konnte mit einer vorgeschlagenen Gleichung beschrieben werden.

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Boček, K., Kopecký, J., Krivucová, M. et al. Chemical structure and biological activity ofp-disubstituted derivatives of benzene. Experientia 20, 667–668 (1964). https://doi.org/10.1007/BF02145258

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