Skip to main content
SpringerLink
Log in

Glycosignals in Cancer

Molecular Assembly and Recognition

  • Book
  • © 2023
  • Latest edition

Overview

Editors:
  1. Koichi Furukawa

    1. Department of Biomedical Sciences, Chubu University College of Life and Health Sciences, Kasugai, Japan

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Minoru Fukuda

    1. Glycobiology Unit, Sanford-Burnham Medical Research Institute, La Jolla, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Provides up-to-date information on glycoscience, linking basic biology and clinical applications
  • Presents new results, approaches, and research directions
  • Ideal guide to the field for students and young researchers

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (10 chapters)

  1. Front Matter

    Pages i-vi
    Download chapter PDF

  2. Search for Novel Tumor Epitopes Related to Carbohydrates

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. The Ganglioside Structures: Chemistry and Biochemistry

      • Laura Mauri, Sandro Sonnino
      Pages 3-17

    3. Fucosylated Proteins as Cancer Biomarkers

      • Eiji Miyoshi, Kazutoshi Fujita, Koichi Morishita, Tsunenori Ouchida, Tsutomu Nakagawa, Shinji Takamatsu et al.
      Pages 19-32

  3. Assembly of Glycoconjugates

    1. Front Matter

      Pages 33-33
      Download chapter PDF

    2. Substantial Basis for Glyco-Assembly: Siglec7 and Synthetic Sialylpolymers

      • Sayo Morishita, Masaya Hane, Ken Kitajima, Chihiro Sato
      Pages 35-52

    3. Role of Sialyl-Tn Antigen in Cancer Metastasis

      • Ruka Ito, Keisuke Nagao, Kazuaki Ohtsubo
      Pages 53-78

    4. Insights into the Role of Chondroitin Sulfate in Cancer

      • Satomi Nadanaka, Hiroshi Kitagawa
      Pages 79-101

  4. Signaling Pathways Modulated by Glycosylation

    1. Front Matter

      Pages 103-103
      Download chapter PDF

    2. Significance of FUT8 in Pancreatic Cancer and Others

      • Caixia Liang, Wanli Song, Jianguo Gu
      Pages 105-124

    3. Effects of Bullfrog Sialic Acid–Binding Lectin in Cancer Cells

      • Takeo Tatsuta, Masahiro Hosono
      Pages 125-147

  5. Interaction Between Carbohydrate and Carbohydrate-Recognizing Molecules

    1. Front Matter

      Pages 149-149
      Download chapter PDF

    2. Opposite Functions of Mono- and Disialylated Glycosphingo-Lipids on the Membrane of Cancer Cells

      • Koichi Furukawa, Yuhsuke Ohmi, Farhana Yesmin, Kazunori Hamamura, Yuji Kondo, Yuki Ohkawa et al.
      Pages 151-169

    3. Tumor Progression through Interaction of Mucins with Lectins and Subsequent Signal Transduction

      • Shungo Iwamoto, Naoki Itano, Hiroshi Nakada
      Pages 171-211

  6. Clinical Trials Targeting Glycosignals

    1. Front Matter

      Pages 213-213
      Download chapter PDF

    2. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond

      • Jung-Tung Hung, Alice L. Yu
      Pages 215-238
Back to top

Keywords

About this book

This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefitfor specialists in the field.


Editors and Affiliations

  • Department of Biomedical Sciences, Chubu University College of Life and Health Sciences, Kasugai, Japan

    Koichi Furukawa

  • Glycobiology Unit, Sanford-Burnham Medical Research Institute, La Jolla, USA

    Minoru Fukuda

About the editors

Koichi Furukawa
College of Life and Health Sciences, Chubu University, Japan


Minoru Fukuda
Cancer Research Center, Standford-Burnham Medical Research Institute La Jolla, CA, USA

Bibliographic Information

  • Book Title: Glycosignals in Cancer

  • Book Subtitle: Molecular Assembly and Recognition

  • Editors: Koichi Furukawa, Minoru Fukuda

  • DOI: https://doi.org/10.1007/978-981-19-7732-9

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2023

  • Hardcover ISBN: 978-981-19-7731-2Published: 21 March 2023

  • Softcover ISBN: 978-981-19-7734-3Published: 22 March 2024

  • eBook ISBN: 978-981-19-7732-9Published: 20 March 2023

  • Edition Number: 2

  • Number of Pages: VI, 238

  • Number of Illustrations: 1 b/w illustrations

  • Topics: Cancer Research, Human Genetics, Biochemistry, general, Cell Biology, Oncology

Publish with us

Policies and ethics

Back to top

Search

Navigation