Overview
- Highlights the role of polyphenols in cancer management
- Reviews molecular mechanisms of modulating signaling pathways by polyphenols in cancer
- Examines polyphenols-enriched seafood in modulating anti- and pro-inflammatory cytokines
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About this book
This book reviews the applications of polyphenols in cancer treatment. The initial chapter of the book classifies different polyphenols and discusses their biological and chemical properties. The subsequent chapters then explore the diverse role of polyphenols in modulating signal transduction pathways in cancer including, cellular proliferation, differentiation, apoptosis, inflammation, angiogenesis, and metastasis. This book highlights the usefulness of polyphenol enriched seafood in modulating the anti-tumor and anti-inflammatory cytokine IFN-γ. The book also presents nanoformulation of polyphenol as a promising strategy for their enhanced bioavailability and targeted delivery. Lastly, the book examines the toxicity and safety evaluations of polyphenols as anticancer agents.
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Keywords
Table of contents (12 chapters)
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Front Matter
Editors and Affiliations
About the editors
Prof. Shams Tabrez is working as a Professor of Biochemistry at King Fahd Medical Research Center, King Abdulaziz University (KAU). Earlier, he has obtained Ph.D. in Biochemistry from Aligarh Muslim University (AMU), India. His research is focused on cancer chemoprevention using bioactive compounds and the improvement of their delivery by nanotechnology-based techniques. He also has a strong research interest in the field of metabolomics and enzymology. He has published more than 130 articles in journals of high repute. Prof. Tabrez is serving and/or served as an editorial board member of several journals, including Current Pharmaceutical Design, Current Clinical Pharmacology, Cells, Current Vascular Pharmacology, and Pharmacognosy Magazine.
Dr. Mohammad Imran Khan is an Associate Professor in the Department of Biochemistry at KAU, Saudi Arabia. He obtained his Ph.D. in Medical Biochemistry from CSIR-Indian Institute of Toxicology Research (CSIR-IITR) and Aligarh Muslim University (AMU), India, and did post-doctoral training from the University of Wisconsin, Madison. His research interest includes nano-chemoprevention, epigenetics, and metabolomics. He has published more than 60 research articles in the journals of international repute.
Dr. Mohammad Imran Khan is an Associate Professor in the Department of Biochemistry at KAU, Saudi Arabia. He obtained his Ph.D. in Medical Biochemistry from CSIR-Indian Institute of Toxicology Research (CSIR-IITR) and Aligarh Muslim University (AMU), India, and did post-doctoral training from the University of Wisconsin, Madison. His research interest includes nano-chemoprevention, epigenetics, and metabolomics. He has published more than 60 research articles in the journals of international repute.
Bibliographic Information
Book Title: Polyphenols-based Nanotherapeutics for Cancer Management
Editors: Shams Tabrez, Mohammad Imran Khan
DOI: https://doi.org/10.1007/978-981-16-4935-6
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive licence to Springer Nature Singapore Pte Ltd. 2021
Hardcover ISBN: 978-981-16-4934-9Published: 02 October 2021
Softcover ISBN: 978-981-16-4937-0Published: 03 October 2022
eBook ISBN: 978-981-16-4935-6Published: 01 October 2021
Edition Number: 1
Number of Pages: XIII, 437
Number of Illustrations: 41 b/w illustrations, 44 illustrations in colour
Topics: Cancer Research, Immunology