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The ultrastructure, catecholamine, and prolactin contents of the rostral pars distalis of the fish Mugil platanus after reserpine or 6-hydroxydopamine administration

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Summary

The rostral pars distalis (RPD) of the teleost Mugil platanus from animals pretreated with reserpine or 6-hydroxydopamine (6-HODA) were assayed for dopamine (DA) or noradrenaline (NA) or for prolactin hormone. Such determinations were coupled with electron microscopy. It was found that reserpine and 6-HODA produced a significant decrease in the content of DA, NA, and prolactin. Electron microscope studies revealed that prolactin cells became activated as judged by ultrastructural criteria. After 6-HODA treatment type “B” neurosecretory fibers entering the RPD became selectively destroyed. These observations lead us to suggest that prolactin secretion is under inhibitory control by type “B” neurosecretory fibers of adrenergic nature.

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References

  • Abraham, M.: The ultrastructure of the cell types and of neurosecretion innervation in the pituitary of Mugil cephalus L. from fresh water, the sea, and hypersaline lagoon. I. The rostral pars distalis. Gen. comp. Endocr. 17, 334–350 (1971)

    Google Scholar 

  • Båge, G., Ekengren, B., Fernholm, B., Pridberg, G.: The pituitary gland of the roach Leuciscus rutilus. I. The rostral pars distalis. Acta zool. (Stockh.) 55, 25–45 (1974)

    Google Scholar 

  • Ball, J. N., Baker, B. I., Olivereau, M., Peter, R. E.: Investigations on hypothalamic control of adenohypophyseal functions in teleost fishes. Gen. comp. Endocr., Suppl. 3, 11–21 (1972)

    Google Scholar 

  • Clarke, W. C.: Disc-electrophoretic identification of prolactin in the cichlid teleosts Tilapia and Cichlasoma and densitometric measurement of its concentration in Tilapia pituitaries during salinity transfer experiments. Canad. J. Zool. 51, 687–695 (1973)

    Google Scholar 

  • Dellmann, H. D.: Degeneration and regeneration of neurosecretory systems. Int. Rev. Cytol. 36, 215–315 (1973)

    Google Scholar 

  • Dharmamba, M., Nishioka, R. S.: Response of “prolactin-secreting” cells of Tilapia mossam- bica to environmental salinity. Gen. comp. Endocr. 10, 409–420 (1968)

    Google Scholar 

  • Follénius, E.: Bases structurales et ultrastructurales des corrélations diencéphalo-hypophysaires chez les Sélaciens et les Téléostéens. Arch. Anat. micr. Morph. exp. 54, 195–216 (1965)

    Google Scholar 

  • Follénius, E.: Innervation adrénergique de la méta-adénohypophyse de l'Epinoche (Gasterosteus aculeatus L.). Mise en évidence par autoradiographie au microscope électronique. C. R. Acad. Sci. (Paris) 267, 1208–1211 (1968)

    Google Scholar 

  • Follénius, E.: Intégration de la dopamine dans les terminaisons aminergiques de la métadénohypophyse de l'Epinoche (Gasterosteus aculeatus L.). C. R. Acad. Sci. (Paris) 273, 1039–1044 (1971)

    Google Scholar 

  • Follénius, E.: Cytologie fine de la dégénérescence des fibres aminergiques intrahypophysaires chez le poisson téléostéen Gaslerosteus aculeatus apres traitement par la 6-hydroxydopamine. Z. Zellforsch. 128, 69–82 (1972)

    Google Scholar 

  • Haggendal, J.: An improved method for fluorometric determination of small amounts of adrenaline and noradrenaline in plasma and tissues. Acta physiol. scand. 59, 242–254 (1963)

    Google Scholar 

  • Hopkins, C. R.: Localization of adrenergic fibers in the amphibian pars intermedia by electron- microscope autoradiography and their selective removal by 6-hydroxydopamine. Gen. comp. Endocr. 16, 112–120 (1971)

    Google Scholar 

  • Ingleton, P. M., Baker, B. I., Ball, J. N.: Secretion of prolactin and growth hormone by teleost pituitaries in vitro. I. Effect of sodium concentration and osmotic pressure during short term incubations. J. comp. Physiol. 87, 317–328 (1973)

    Google Scholar 

  • Knowles, F. G. W.: Evidence for a dual control by neurosecretion, of hormone synthesis and hormone release in the pituitary of the dogfish, Scyliorhinus stellaris. Phil. Trans. B 249, 435–455 (1965)

    Google Scholar 

  • Lagios, M. D.: The median eminence of the bowfin, Amia calva L. Gen. comp. Endocr. 15, 453–463 (1970)

    Google Scholar 

  • Laverty, R., Taylor, K. M.: The fluorometric assay of catecholamines and related compounds: Improvements and extensions to the hydroxyindole technique. Analyt. Biochem. 22, 269–279 (1968)

    Google Scholar 

  • Malmfors, T., Sachs, Ch.: Degeneration of adrenergic nerves by 6-hydroxydopamine. Europ. J. Pharmacol. 3, 89–92 (1968)

    Google Scholar 

  • Nagahama, Y., Nishioka, R. S., Bern, H. A.: Responses of prolactin cells of two euryhaline marine fishes, Gillichthys mirabilis and Platichthys stllatus, to environmental salinity. Z. Zellforsch. 136, 153–167 (1973a)

    Google Scholar 

  • Nagahama, Y., Nishioka, R. S., Bern, H. A.: Structure and function of the transplanted pituitary in the seawater goby, Gillichthys mirabilis. I. The rostral pars distalis. Gen. comp. Endocr. 22, 21–34 (1974)

    Google Scholar 

  • Olivereau, M.: Action de la réserpine chez l'Anguille. I. Cellules à prolactine de l'hypophyse du male. Z. Zellforsch. 121, 232–243 (1971)

    Google Scholar 

  • Olivereau, M.: Action de la réserpine chez l'Anguille. II. Effet sur la pigméntation et le lobe intérmediaire. Comparison avec l'effet de l'adaptation sur un fond noir. Z. Anat. Entwickl. Gesch. 137, 30–46 (1972)

    Google Scholar 

  • Peter, R. E.: Hypothalamic control of thyroid gland activity and gonadal activity in the goldfish, Carassius auratus. Gen. comp. Endocr. 14, 334–356 (1970)

    Google Scholar 

  • Richards, J. G., Tranzer, J. P.: The ultrastructural localization of amine storage sites in the central nervous system with the aid of a specific marker, 5-hydroxydopamine. Brain Res. 17, 463–469 (1970)

    Google Scholar 

  • Sage, M.: Organ culture of teleost pituitaries. J. Endocrinol. 34, ix-x (1966)

    Google Scholar 

  • Sage, M.: Responses to osmotic stimuli of Xiphophorus prolactin cells in organ culture. Gen. comp. Endocr. 10, 70–74 (1968)

    Google Scholar 

  • Sage, M.: Control of prolactin release and its role in color change in the teleost Gillichthys mirabilis. J. exp. Zool. 173, 121–128 (1970)

    Google Scholar 

  • Sulser, F., Sanders-Bush, E.: Effect of drugs on amines in the central nervous system. Ann. Rev. Pharmacol. 11, 209–230 (1971)

    Google Scholar 

  • Sundararaj, B. I., Nayyar, S. K.: Effect of prolactin on the ‘seminal vesicles’ and neural regulation of prolactin secretion in the catfish Heteropneustes fossilis (Bloch). Gen. comp. Endocr., Suppl 2, 69–80 (1969)

    Google Scholar 

  • Thoenen, M., Tranzer, J.-P.: Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-hydroxydopamine. Arch. exp. Path. 261, 271–288 (1968)

    Google Scholar 

  • Thoenen, M., Tranzer, J.-P., Hausler, G.: Chemical sympathectomy with 6-hydroxydopamine. In: New aspects of storage and release mechanisms of catecholamines. Bayer Symp., vol. 2, p. 130–142. Berlin-Heidelberg-New York: Springer 1970

    Google Scholar 

  • Tranzer, J. P.: Discussion of the mechanisms of action of 6-hydroxydopamine on peripheral neurons. In: 6-Hydroxydopamine and catecholamine neurons. Malmfors, T. and Thoenen, U. (eds.), p. 257–264. Amsterdam: North Holland 1971

    Google Scholar 

  • Ungerstedt, U.: Histochemical studies on the effect of intracerebral and intraventricular injections of 6-hydroxydopamine on monoamine neurons in the rat brain. In: 6-Hydroxydopamine and catecholamine neurons in the rat brain. Malmfors, T. and Thoenen, M. (eds.), p. 101–127. Amsterdam: North Holland 1971

    Google Scholar 

  • Uretsky, N. J., Iversen, L. L.: Effects of 6-hydroxydopamine on catecholamine containing neurons in the rat brain. J. Neurochem. 17, 269–278 (1970)

    Google Scholar 

  • Zambrano, D.: The nucleus lateralis tuberis system of the gobiid fish Gillichthys mirabilis. II. Innervation of the pituitary. Z. Zellforsch. 110, 496–516 (1970)

    Google Scholar 

  • Zambrano, D.: Innervation of the teleost pituitary. Gen. comp. Endocr., Suppl. 3, 22–31 (1972)

    Google Scholar 

  • Zambrano, D., Clarke, W. C., Hawkins, E. F., Sage, M., Bern, H. A.: Influence of 6-hydroxydopamine on hypothalamic control of prolactin and ACTH secretion in the teleost fish, Tilapia mossambica. Neuroendocrinology 13, 284–298 (1974)

    Google Scholar 

  • Zambrano, D., Iturriza, F. I.: Hypothalamic-hypophysial relationships in the South American lungfish Lepidosiren paradoxa. Gen. comp. Endocr. 20, 256–273 (1973)

    Google Scholar 

  • Zambrano, D., Nishioka, R. S., Bern, H. A.: The innervation of the pituitary gland of teleost fishes. In: Brain-endocrine interaction. Median eminence: Structure and function. Knigge, K., Scott, D. E., and Weindl, A. (eds.), p. 50–66. Basel: A. G. Karger 1971

    Google Scholar 

  • Zanini, A., Giannattasio, G.: Isolation of prolactin granules from rat anterior pituitary glands. Endocrinology 92, 349–357 (1973)

    Google Scholar 

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  1. Departamento de Cienoias Biológicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina

    David Zambrano

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  1. David Zambrano
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Member of the Scientific Career, Consejo Nacional de Investigaciones Científicas y Técnicas, Argentina.

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Zambrano, D. The ultrastructure, catecholamine, and prolactin contents of the rostral pars distalis of the fish Mugil platanus after reserpine or 6-hydroxydopamine administration. Cell Tissue Res. 162, 551–563 (1975). https://doi.org/10.1007/BF00209354

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  • DOI: https://doi.org/10.1007/BF00209354

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