ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] A library of 62 thrombin mutants11, in which the solvent-exposed charged and polar amino acids were substituted with alanine, was screened for mutants that were defective in fibrin-ogen clotting yet retained their ability to activate protein C in the presence of thrombomodulin. One mutation, E229A, ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/378413a0
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