Publication Date:
1981-03-27
Description:
Open-chest, anesthetized dogs with occlusions of the left anterior descending coronary artery breathed 100 percent oxygen while they were bled to a hematocrit of 25 percent and infused with an approximately equal volume (40 milliliters per kilogram) of fluorocarbon preparation or Ringer solution. Dogs breathing room air and receiving no treatment served as controls. After undergoing 6 hours of coronary occlusion, animals bled and treated with fluorocarbons developed smaller infarctions than those receiving Ringer solution or no treatment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Glogar, D H -- Kloner, R A -- Muller, J -- DeBoer, L W -- Braunwald, E -- Clark, L C Jr -- HL-26215/HL/NHLBI NIH HHS/ -- R01-HL-23140/HL/NHLBI NIH HHS/ -- R01-HL-23526/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1981 Mar 27;211(4489):1439-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466402" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Constriction
;
Coronary Disease/*prevention & control
;
Coronary Vessels/physiology
;
Dogs
;
Fluorocarbons/*therapeutic use
;
Myocardial Infarction/pathology/prevention & control
;
Myocardium/pathology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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