ISSN:
1612-1112
Schlagwort(e):
High-performance TLC
;
Sulfonamides
;
Rf values
;
Densitometry
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Summary Rf values of twenty therapeutic sulfonamides have been estimated in seven solvent systems. Based on these data a simple identification scheme was developed demanding only three solvent systems for complete separation. Quantification of corresponding fluorescamine derivatives at nanogram level was performed by the use of an TLC-scanner configured online with a microcomputer. Mathematical treatment of standard curves using the computer program Curve Fitter are discussed. Validity and reproducibility of results are compared with data obtained by HPLC and show good correlation.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02257291
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