ISSN:
1432-072X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary 1. The formation of valine from acetone and glycine and from propan-2-ol and glycine was demonstrated. The transformation of propan-2-ol to acetone was suggested. 2. Acetone, propan-2-ol, glycine, valine and cysteine stimulated the biosynthesis of 6-APA when supplemented separately to the medium. These compounds are arranged in a descending order with respect to their stimulative influence. 3. Coenzyme A influenced favourably the formation of 6-APA. 4. A mixture of acetone, glycine, and cysteine was the most stimulative among the other combinations tried. 5. A presumed sequence of reactions between acetone, glycine and cysteine, probably involving CoA, was thus suggested for the biosynthesis of 6-APA. The reactions involve dehydration and dehydrogenation with the liberation of two molecules of water and two hydrogen atoms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00408548
Permalink