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  • 1
    Online Resource
    Online Resource
    Metropolitan Landscapes : Towards a Shared Construction of the Resilient City of the Future (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Landscape architecture. ; Landscape ecology. ; Geography. ; Environmental Law. ; Geographic information systems. ; Landscape Architecture. ; Landscape Ecology. ; Regional Geography. ; Environmental Law. ; Geographical Information System.
    Description / Table of Contents: Section A – The new cultural perspective -- Section B – The Tool -- Section C – The good practices.
    Abstract: This edited volume covers many aspects of the Metropolitan Landscapes. Solutions are needed to meet the demand of the citizens of a renewed metropolitan region landscape. It opens up discussions about possible toolkits for strategic actions based on understanding the territory from geographical, urban, architectural, economic, environmental, and public policy perspectives. This book intends to promote the Metropolitan dwelling quality, ensuring human well-being proposing a discussion on the resilient articulation of the interface space among the city's infrastructure, agriculture, and nature. This book results from the Symposium: Metropolitan Landscapes that MSLab of the Politecnico di Milano and ETSA (Sevilla) organized at the IALE 2019 Conference (Milan, July 2019) to manage radical territory transformation with a strategic vision. The widespread growth of urban areas indicates the importance of building resilient sustainable cities capable of minimizing climate-change impact production. The Symposium aimed to discuss the Urban Metabolism approach considering the combination of Landscapes set in a single Metropolitan Ecosystem. Accordingly, new design strategies of transformation, replacement or maintenance can compose Urban-Rural Linkage patterns and a decalage of different landscape contexts. Ecological interest in environmental sustainability, compatibility, and resilience is not tied exclusively to the balance between production and energy consumption. Thus, it is the integration over time and at several scales of the urban and rural landscapes and their inhabitants that nourish the Metropolitan Bioregion. Moreover, the Metropolitan Landscape Book's research hypothesis is the need for a Glossary, strengthening the basis of understanding Metropolitan Landscape's complexity. This book's topic is particularly relevant to Landscape Urbanism, Architecture, Urban disciplines Scholars, Students and Practitioners who want to be connected in a significant way with Metropolitan Discipline’s research field.
    Type of Medium: Online Resource
    Pages: XVI, 191 p. 77 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030744243
    Series Statement: Landscape Series, 28
    URL: https://doi.org/10.1007/978-3-030-74424-3
    DOI: 10.1007/978-3-030-74424-3
    DDC: 710
    Language: English
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    E-BOOKS (AWI ONLY)
  • 2
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    The HEPD particle detector and the EFD electric field detector for the CSES satellite (2018)
    Details
    Publication Date: 2021-09-20
    Description: The CSES satellite, developed by Chinese (CNSA) and Italian (ASI) space Agencies, will investigate iono-magnetospheric disturbances (induced by seismicity and electromagnetic emissions of tropospheric and anthropogenic origin); will monitor the temporal stability of the inner Van Allen radiation belts and will study the solar-terrestrial coupling by measuring fluxes of cosmic rays and solar energetic particles. In particular the mission aims at confirming the existences (claimed from several analyses) of a temporal correlations between the occurrence of earthquakes and the observation in space of electromagnetic disturbances, plasma fluctiations and anomalous fluxes of high-energy particles precipitating from the inner Van Allen belt. CSES will be launched in the summer of 2017 with a multi-instruments payload able to measure: e.m. fields, charged particles, plasma, TEC, etc. The Italian LIMADOU collaboration will provide the High-Energy Particle Detector (HEPD), designed for detecting electrons (3–200 MeV) and proton (30–300 MeV)), and participates to develop the Electric Field Detector (EFD) conceived for measuring electric field from ∼DC up to 5 MHz.
    Description: Published
    Description: 187-192
    Description: 4T. Sismologia, geofisica e geologia per l'ingegneria sismica
    Description: 2A. Fisica dell'alta atmosfera
    Description: JCR Journal
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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    PAPER (OA)
  • 3
    Electronic Resource
    Electronic Resource
    Influence of inorganic and organic fertilization on soil microbial biomass, metabolic quotient and heavy metal bioavailability (1999)
    Springer
    Biology and fertility of soils 28 (1999), S. 371-376 
    Details
    ISSN: 1432-0789
    Keywords: Key words Organic fertilization ; Soil microbial biomass carbon ; Metabolic quotient ; Bioavailability ; Heavy metals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract  We studied the long-term effects (12 years) of municipal refuse compost addition on the total organic carbon (TOC), the amount and activity of the microbial biomass (soil microbial biomass C, BC and metabolic quotient qCO2) and heavy metal bioavaiability in soils as compared to manuring with mineral fertilizers (NPK) and farmyard manure (FYM). In addition, we studied the relationships between among the available fraction [Diethylenetriaminopentacetic acid (DTPA) extractable] of heavy metals and their total content, TOC and BC. After 12 years of repeated treatments, the TOC and BC of control and mineral fertilized plots did not differ. Soils treated with FYM and composts showed a significant increase in TOC and BC in response to the increasing amounts of organic C added. Values of the BC/TOC ratio ranged from 1.4 to 2, without any significative differences among soil treatments. The qCO2 increased in the organic-amended soil and may have indicated microbial stress. The total amounts of metals in treated soils were lower than the levels permitted by the European Union in agricultural soils. DTPA-extractable metals increased in amended soils in response to organic C. A multiple regression analysis with stepwise selection of variables was carried out in order to discriminate between the influence exerted on DTPA-extractable metals by their total content, TOC and BC. Results showed that each metal behaved quite differently, suggesting that different mechanisms might be involved in metal bioavailability
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003740050506
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  • 4
    Electronic Resource
    Electronic Resource
    Effect of meal timing on the kinetic-dynamic profile of levodopa/carbidopa controlled is release in parkinsonian patients (1998)
    Springer
    European journal of clinical pharmacology 54 (1998), S. 303-308 
    Details
    ISSN: 1432-1041
    Keywords: Key words Levodopa ; Controlled release formulations ; Parkinson's disease ; Meal interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: The aim of the study was to assess the effect of the time of ingestion of a meal on the pharmacokinetics and pharmacodynamics of a levodopa/carbidopa controlled-release formulation in parkinsonian patients on chronic levodopa therapy. Methods: The kinetic-dynamic profile of one tablet of controlled-release levodopa/carbidopa 200/50 mg was monitored in eight patients, according to an intrasubject randomized cross-over design in two different sessions. A standard meal was consumed by the patients after they had fasted for 15–17 h, on one occasion 30 min before the ingestion of the test dose, and on the other occasion 2 h after the ingestion of the same drug dose. Blood venous samples for analysis of plasma levodopa and its metabolite 3-O-methyldopa were drawn at 20-min intervals up to 6 h after dosing. Motor response to the levodopa test dose was assessed by the finger tapping and walking speed tests at the same times as blood was drawn. Results: Controlled is release levodopa intake after meals resulted in a significant delay in drug absorption, with an almost twofold increase in time of initial appearance of levodopa in plasma and time to peak plasma concentration. Peak plasma drug concentrations were not significantly different in the two experimental conditions; the area under the 6-h plasma concentration-time curve showed an average reduction of 24% in the fed condition, partly reflecting the incomplete assessment of levodopa absorption, within the 6 h of examination, due␣to 5-h delayed peak plasma levodopa concentration␣in two patients. With reference to levodopa pharmacodynamics, time to onset of motor response was significantly delayed and duration of motor response significantly curtailed in the fed condition, while the magnitude and overall extent of motor effect were unchanged. Conclusions: In keeping with previous findings on levodopa standard-release preparations, these data show that time of meal ingestion is an important determinant of levodopa disposition, even from controlled-release preparations in parkinsonian patients. From a clinical point of view, these results help to explain some of the delayed, curtailed and even lacking responses that often complicate afternoon motor performances in patients at the more advanced stages of the disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050464
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  • 5
    Electronic Resource
    Electronic Resource
    Alpha1-acid glycoprotein concentration and serum protein binding of carbamazepine and carbamazepine-10,11 epoxide in children with epilepsy (1985)
    Springer
    European journal of clinical pharmacology 29 (1985), S. 211-214 
    Details
    ISSN: 1432-1041
    Keywords: carbamazepine ; epilepsy ; carbamazepine-10,11 epoxide ; alpha1-acid glycoprotein ; serum protein binding ; children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The relationship between the serum protein binding of carbamazepine (CBZ) and carbamazepine-10,11 epoxide (CBZ-E) and the concentration of α1-acid glycoprotein (AAG) and albumin (HSA) was examined in 39 CBZ-treated epileptic children aged 4 months to 12 years. A significant inverse correlation was found between the free fraction of both compounds and serum AAG, even though changes in AAG concentration explained only part of the variation in binding. No correlation was found between the free fraction of CBZ and CBZ-E and HSA, probably due to the small intersubject variation in HSA concentration. In vitro experiments showed that both CBZ and CBZ-E were bound to HSA and to a lesser extent to AAG. At equivalent HSA concentrations, the binding of CBZ and its metabolite increased proportionately with increasing AAG concentration within the range occurring clinically.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00547424
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  • 6
    Electronic Resource
    Electronic Resource
    Altered serum protein binding of carbamazepine in disease states associated with an increasedα 1-acid glycoprotein concentration (1986)
    Springer
    European journal of clinical pharmacology 31 (1986), S. 85-89 
    Details
    ISSN: 1432-1041
    Keywords: carbamazepine ; serum protein binding ; alpha1-acid glycoprotein ; albumin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The protein binding of carbamazepine (CBZ) in vitro was assessed in sera from 47 patients with various diseases known to alterα 1-acid glycoprotein (AAG) concentration and from 20 drug-free normal control subjects. In the patient group, AAG and albumin (HSA) concentrations ranged from 6 to 74 µmol/l and from 377 to 652 µmol/l, respectively; in the controls, protein concentrations were less variable, ranging from 11 to 26 µmol/l for AAG and from 623 to 754 µmol/l for HSA. In both the patient and the combined patient and control groups, free CBZ fractions were inversely correlated with the serum AAG concentration (r=−0.62). No significant relationship could be found between the free CBZ fraction and the serum HSA concentration. The free CBZ fraction was moderately but significantly decreased in patients with AAG levels above 26 µmol/l (the highest value found in controls) as compared either to patients with a normal AAG concentration or to control subjects (19±5% vs 23±4% and 23±2%), despite the finding of a higher HSA concentration in the control group. The data confirm AAG as an important determinant of interindividual variability in serum CBZ binding.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00870992
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of age on the pharmacokinetics of oral levodopa in patients with Parkinson's disease (1991)
    Springer
    European journal of clinical pharmacology 41 (1991), S. 463-466 
    Details
    ISSN: 1432-1041
    Keywords: Levodopa ; Pharmacokinetics ; Parkinson's disease ; age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The influence of age on the kinetics of a standard oral dose of levodopa administered with an inhibitor of peripheral dopa decarboxylase enzymes (benserazide) has been evaluated in 40 patients with Parkinson's disease (age 34–78 y) on chronic therapy. They were divided into 2 groups, on the basis of age below (21 patients, Group A) or above (19 patients, Group B) 65 y. The area under the plasma concentration-time curve (AUC) of levodopa was significantly greater in the older group (547 versus 428 μmol·1−1·min in Group B), coupled with a reduced apparent oral clearance (8.1 versus 10.7 ml·min−1 ·kg−1) and a longer plasma elimination half-life (67.6 versus 54.6 min). The age of the patients was positively correlated with the AUC of levodopa (r=0.474) and its plasma elimination half-life (r=0.391), and was negatively correlated with clearance (r=−0.489). The findings confirm previous data on volunteers that showed a reduction in the systemic clearance of levodopa due to age, which would probably account for the finding of a greater AUC of levodopa in older patients. The observed, age-mediated differences in levodopa pharmacokinetics, albeit statistically significant, were moderate and were likely to be of only minor importance for the dosing schedule.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00626370
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  • 8
    Electronic Resource
    Electronic Resource
    Structure of volcanic glasses from the NMR-EPR perspective: a preliminary application to the Neapolitan Yellow Tuff (1999)
    Springer
    Bulletin of volcanology 60 (1999), S. 425-431 
    Details
    ISSN: 1432-0819
    Keywords: Key words Nuclear magnetic resonance ; Electron paramagnetic resonance ; Volcanic glasses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Glass samples from alkali-trachytic pumice of the Lower Member (LM, level LM1) and Upper Member (UM) of the Neapolitan Yellow Tuff at Campi Flegrei Caldera were studied by nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) spectroscopy. The EPR data show that the relative occupancy of the different iron sites varies in samples from the Lower Member LM1 and Upper Member of the eruptive sequence. The LM1 glasses are characterized by a more homogeneous distribution of the cationic site population of iron compared with UM and by a different Fe3+/Al3+ substitution in the C2v symmetrical sites of the silicate framework. 29Si MAS NMR spectra on glasses indicate that LM1 glasses are more depolymerized than UM glasses, indicating the existence of structurally distinct magma batches. 27Al MAS NMR spectra indicate the occurrence in UM glasses of aluminum in both tetrahedral and octahedral coordination; the observed AlVI is believed to be a primary feature of the glass, since 27Al CP-MAS NMR experiments do not reveal detectable esa-hydrated Al. The Al in sixfold coordination could be ascribed either to the more abundant alkali–OH terminations in UM, in which alkalies would be extracted from their charge-balance role for Al, thus altering its fourfold structural position, or to permanent compaction during fast cooling and decompression of high-pressure melts. 23Na CP-MAS NMR experiments indicate the existence of Na–OH groups in both LM1 and UM glasses, relatively more abundant in the latter. Although preliminary, the results indicate the possible application of atomic-scale studies to variables that determine the regimes of explosive volcanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004450050242
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  • 9
    Electronic Resource
    Electronic Resource
    Single muon angular distributions observed in the LVD particle astrophysics experiment
    Amsterdam : Elsevier
    Astroparticle Physics 2 (1994), S. 103-116 
    Details
    ISSN: 0927-6505
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0927-6505(94)90033-7
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  • 10
    Electronic Resource
    Electronic Resource
    Comparison of energy flows in deep inelastic scattering events with and without a large rapidity gap
    Amsterdam : Elsevier
    Physics Letters B 338 (1994), S. 483-496 
    Details
    ISSN: 0370-2693
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0370-2693(94)90804-4
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