ISSN:
0947-3440
Keywords:
Ring transformation
;
Nitrogen heterocycles
;
Cyclizations
;
Substituted 5-[2-(N-phenylsulfamoyl)vinyl]-pyrimidines
;
Masked 1,3-dicarbonyl compounds
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
As a masked 1,3-dicarbonyl compound, the 1,1-dioxo-2H-1,2-thiazine-4-carbaldehyde 1 undergoes ring transformation with amidines to produce 2-substituted 4-methyl-5-[1-methyl-2-methylthio-2-(N-phenylsulfamoyl)vinyl]pyrimidines 3a-f. For 3b, an X-ray structure analysis is reported. From the 4-methyl-2-methylthio-5-[1-methyl-2-methylthio-2-(N-phenylsulfamoyl)vinyl]pyrimidine (3e), the substituted pyrimidinone 4 is obtained by acidic hydrolysis.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199719971230
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