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  • 1
    Electronic Resource
    Electronic Resource
    Spectroscopic Study of Electron Transfer in a Trifunctional Lysine with Anthraquinone as the Electron Acceptor (1994)
    s.l. : American Chemical Society
    Inorganic chemistry 33 (1994), S. 2974-2983 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic00091a042
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  • 2
    Electronic Resource
    Electronic Resource
    Redox-active crown ethers. Electrochemical and electron paramagnetic resonance studies on alkali metal complexes of quinone crown ethers (1992)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 114 (1992), S. 8983-8991 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00049a032
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  • 3
    Electronic Resource
    Electronic Resource
    Photoinduced electron transfer in amino acid assemblies (1993)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 115 (1993), S. 5479-5495 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00066a017
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  • 4
    Electronic Resource
    Electronic Resource
    Can marine mammals be used to monitor oceanographic conditions? (1999)
    Springer
    Marine biology 134 (1999), S. 387-395 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The breeding performance of higher predators has often been used to monitor fluctuations in the abundance of important prey stocks in marine ecosystems. The development of electronic data-loggers in recent years has also provided the opportunity of using wide-ranging marine animals to measure physical oceanographic conditions. In this study, time–depth recorders (TDRs) programmed to record temperature were deployed on female Antarctic fur seals (Arctocephalus gazella) at Bird Island, South Georgia (54°00′S; 38°02′W) during the breeding seasons 1994 to 1998. Temperature sensors had relatively slow response times, and thermal radiation errors occurred during the day when seals spent a large proportion of their time at the surface. Nevertheless, measurements provided temperature–depth profiles which were typical of the vertical stratification of the ocean. During the early stages of a foraging trip temperature increased, suggesting that fur seals travelled northwards from South Georgia towards the warmer waters of the Polar Front. In addition, higher temperatures were recorded by females that remained at sea for longer, implying that these individuals also travelled further. Mean sea-surface temperature (SST) increased from ∼1 to 4 °C from December to March and agreed with SSTs from ship, buoy and satellite. Future studies on marine mammals which combine satellite tracking with oceanographic measurements are likely to provide valuable information on biophysical aspects of the ocean.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002270050555
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  • 5
    Electronic Resource
    Electronic Resource
    Mapping of the genes for tubular basement membrane antigen and a submaxillary gland protease in the rat (1984)
    Springer
    Immunogenetics 20 (1984), S. 117-123 
    Details
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The gene for tubular basement membrane (Tbm) antigen in the rat has been mapped relative to other markers in the first linkage group, and a polymorphic locus for a submaxillary gland protease, Tamase-1, has been identified. The hair-loss mutation fuzzy has also been mapped and occupies a position which is similar to that of the frizzy gene in the mouse. There are now at least five, and possibly six, genetic loci distributed over more than 30 centimorgans in the first linkage group of the rat which map in positions of approximate homology on the seventh chromosome of the mouse.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00364483
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  • 6
    Electronic Resource
    Electronic Resource
    Polymorphism of genes involved in anti-tubular basement membrane disease in rats (1983)
    Springer
    Immunogenetics 17 (1983), S. 55-65 
    Details
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Inbred strains of rats differ widely in their susceptibility to interstitial nephritis induced by rabbit renal tubular basement membrane (TBM) preparations. We now report that susceptibility is determined in part by an RTI-linked gene for effector cell responsiveness producing interstitial lesions. Furthermore we also obtained evidence that the gene determining expression of the target TBM antigen is linked to the gene for albinism on the first linkage group. When non-susceptible rats lacking the TBM antigen but having the gene for cellular responsiveness were mated with non-susceptible rats which had the TBM antigen but lacked the gene for cellular responsiveness, the F1 hybrids were susceptible to the induction of interstitial nephritis. Although strains varied widely in the amount of anti-TBM antibody (αTBM-Ab) they produced, this variation does not appear to be controlled by RTI-linked genes, nor does the isotype or amount of antibody appear to be related to the susceptibility to infiltrating cellular lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00364289
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  • 7
    Electronic Resource
    Electronic Resource
    Bioavailability of oral dexamethasone during high dose steroid therapy in neurological patients (1983)
    Springer
    European journal of clinical pharmacology 24 (1983), S. 103-108 
    Details
    ISSN: 1432-1041
    Keywords: dexamethasone ; bioavailability ; pharmacokinetics ; ‘first-pass’ effect ; pre-systemic elimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics and oral biovailability of dexamethasone were studied in 6 patients with neurological disease being treated with high dosages of the drug. A specific high performance liquid chromatographic assay was used to measure dexamethasone concentrations. Unlike the previously published mean figure of 0.78 for the oral bioavailability of the drug given in single doses to healthy volunteers, the mean bioavailability of dexamethasone in the patients studied was 0.53±SD 0.40. It appeared more likely that this incomplete bioavailability was due to presystemic elimination than to poor absorption. The intravenous clearance of the drug was relatively high (0.4902±SD 2291 l kg−1, approximately 65% of expected hepatic plasma flow), the oral clearance higher (2.5804±SD 3.2181 l kg−1 h−1) while the absorption rate constant (4.8729±8.4998 h−1), suggested rapid absorption after oral administration. Prior phenytoin and possibly prior dexamethasone therapy is likely to have contributed to the higher clearance values of the drug in these patients than the values reported in healthy volunteers after single dose studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00613935
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  • 8
    Electronic Resource
    Electronic Resource
    Identification of three ubiquitin genes of the rice blast fungus Magnaporthe grisea, one of which is highly expressed during initial stages of plant colonisation (1998)
    Springer
    Current genetics 33 (1998), S. 352-361 
    Details
    ISSN: 1432-0983
    Keywords: Key wordsPyricularia oryzae ; Ribosomal biosynthesis ; Gene amplification ; Plant infection ; Fungal pathogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Differential cDNA screening was used to identify genes expressed during the colonisation of rice leaves by the pathogenic fungus Magnaporthe grisea. This led to the identification of a gene, called UEP1, which encodes a ubiquitin extension protein. UEP1 was highly expressed 48 h after initial fungal infection of rice leaves when M. grisea is proliferating in the leaf epidermis but not yet causing disease symptoms. UEP1 appeared to be down-regulated after this time despite further extensive growth of the fungus throughout the leaf tissue. To investigate the potential role of ubiquitin in fungal pathogenesis we subsequently isolated UEP3 and PUB4, encoding a second ubiquitin extension protein and a polyubiquitin respectively. UEP1 was expressed abundantly during active growth of M. grisea in axenic culture but was down-regulated by starvation-stress. UEP3 showed a similar pattern of expression to UEP1 during the growth of M. grisea in culture and after environmental stress, but was not highly expressed during plant colonisation. PUB4 was highly expressed after environmental stress, but was not highly expressed during plant colonisation. UEP1 was found to be present in a much-higher copy number per haploid genome compared to UEP3 and PUB4. The restricted high-level expression of UEP1 suggests that M. grisea undergoes rapid ribosomal biogenesis and protein turnover during initial plant-tissue colonisation, which is regulated by a specific UEP1-encoded component of the M. grisea ubiquitin gene family.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002940050347
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  • 9
    Electronic Resource
    Electronic Resource
    Derelict land reclamation and English Partnerships - shedding light on the new regime (1996)
    Bingley : Emerald
    Property management 14 (1996), S. 10-16 
    Details
    ISSN: 0263-7472
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Explains that the 1993 Department of Environment Survey of Derelict Land in England found that the area of derelict land in England between 1988 and 1993 remained relatively static, despite the considerable sums of public money spent on derelict land reclamation during this period. With the launch of English Partnerships in 1993, and its subsuming of Derelict Land Grant the following year, evaluates the changes in the funding of derelict land reclamation in England and attempts to identify the likely outcomes of such changes. Describes a study in which key players within English Partnerships and Government Offices for the regions were interviewed, as well as local government officers with the responsibility for implementing land reclamation programmes. Concludes that there will be a reduction in the priority and funding of derelict land reclamation and that as a consequence, the area of derelict land in England may increase for the first time in over a decade.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/02637479610124945
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  • 10
    Electronic Resource
    Electronic Resource
    Effects of Vacuum Hydration on the Incidence of Splits in Canned Kidney Beans (Phaseolus vulgaris) (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 50 (1985), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Dry red kidney beans were canned using two different pretreatments: soaking for 12 hr at 20°C, and vacuum hydration for 5 min followed by soaking for 2 hr at temperatures from 45-59.1°C. Samples were then packed, processed to commercial sterility, and tested for percentage of split beans after processing. Vacuum hydration pretreatments greatly decreased the incidence and severity of splitting in the canned product and accelerated water uptake while retaining the same moisture content after soaking as the conventional soak treatment. Vacuum-hydrated beans gained less moisture during retorting than conventionally treated samples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1985.tb10513.x
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