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  • 1
    Monograph available for loan
    Monograph available for loan
    Control Surveys in civil engineering (1987)
    New York : Nichols
    Details Availability
    Call number: M 12.0218
    Type of Medium: Monograph available for loan
    Pages: xiii, 381 S.
    ISBN: 089397272X
    Classification:
    Geodetic Theory and Modeling
    Location: Upper compact magazine
    Branch Library: GFZ Library
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  • 2
    Monograph available for loan
    Monograph available for loan
    Fundamentals of survey measurement and analysis (1974)
    London : Crosby Lockwood Staples
    Details Availability
    Call number: O 4387
    Type of Medium: Monograph available for loan
    Pages: 107 S. : graph. Darst.
    Series Statement: Aspects of modern land surveying
    Location: Upper compact magazine
    Branch Library: GFZ Library
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  • 3
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    Inversion Tectonics (1989)
    Oxford, London, Edinburgh, Boston, Melbourne : Blackwell Scientific Publications
    Details
    Keywords: Aufschiebung ; Überschiebung ; Tektonik ; Erdkruste ; Inversions (Geology)
    Description / Table of Contents: M. A. Cooper and G. D. Williams: Introduction / Geological Society, London, Special Publications, 44:vii, doi:10.1144/GSL.SP.1989.044.01.01 --- Modelling and Theoretical Concepts --- G. D. Williams, C. M. Powell, and M. A. Cooper: Geometry and kinematics of inversion tectonics / Geological Society, London, Special Publications, 44:3-15, doi:10.1144/GSL.SP.1989.044.01.02 --- A. B. Hayward and R. H. Graham: Some geometrical characteristics of inversion / Geological Society, London, Special Publications, 44:17-39, doi:10.1144/GSL.SP.1989.044.01.03 --- K. R. McClay: Analogue models of inversion tectonics / Geological Society, London, Special Publications, 44:41-59, doi:10.1144/GSL.SP.1989.044.01.04 --- Inversion in the Alps and Alpine Foreland --- P. A. Ziegler: Geodynamic model for Alpine intra-plate compressional deformation in Western and Central Europe / Geological Society, London, Special Publications, 44:63-85, doi:10.1144/GSL.SP.1989.044.01.05 --- P. C. de Graciansky, G. Dardeau, M. Lemoine, and P. Tricart: The inverted margin of the French Alps and foreland basin inversion / Geological Society, London, Special Publications, 44:87-104, doi:10.1144/GSL.SP.1989.044.01.06 --- R. W. H. Butler: The influence of pre-existing basin structure on thrust system evolution in the Western Alps / Geological Society, London, Special Publications, 44:105-122, doi:10.1144/GSL.SP.1989.044.01.07 --- I. R. Simpson, M. Gravestock, D. Ham, H. Leach, and S. D. Thompson: Notes and cross-sections illustrating inversion tectonics in the Wessex Basin / Geological Society, London, Special Publications, 44:123-129, doi:10.1144/GSL.SP.1989.044.01.08 --- D. G. Roberts: Basin inversion in and around the British Isles / Geological Society, London, Special Publications, 44:131-150, doi:10.1144/GSL.SP.1989.044.01.09 --- Inversion on the European Continental Shelf --- J. A. Cartwright: The kinematics of inversion in the Danish Central Graben / Geological Society, London, Special Publications, 44:153-175, doi:10.1144/GSL.SP.1989.044.01.10 --- T. J. Chapman: The Permian to Cretaceous structural evolution of the Western Approaches Basin (Melville sub-basin), UK / Geological Society, London, Special Publications, 44:177-200, doi:10.1144/GSL.SP.1989.044.01.11 --- M. E. Badley, J. D. Price, and L. C. Backshall: Inversion, reactivated faults and related structures: seismic examples from the southern North Sea / Geological Society, London, Special Publications, 44:201-219, doi:10.1144/GSL.SP.1989.044.01.12 --- Inversion in Other Geological Environments --- C. M. Powell and G. D. Williams: The Lewis Thrust/Rocky Mountain trench fault system in Northwest Montana, USA: an example of negative inversion tectonics? / Geological Society, London, Special Publications, 44:223-234, doi:10.1144/GSL.SP.1989.044.01.13 --- K. R. McClay, M. W. Insley, and R. Anderton: Inversion of the Kechika Trough, Northeastern British Columbia, Canada / Geological Society, London, Special Publications, 44:235-257, doi:10.1144/GSL.SP.1989.044.01.14 --- C. K. Morley: Basin inversion in the Osen-Røa thrust sheet, Southern Norway / Geological Society, London, Special Publications, 44:259-273, doi:10.1144/GSL.SP.1989.044.01.15 --- M. P. Coward, M. A. Enfield, and M. W. Fischer: Devonian basins of Northern Scotland: extension and inversion related to Late Caledonian — Variscan tectonics / Geological Society, London, Special Publications, 44:275-308, doi:10.1144/GSL.SP.1989.044.01.16 --- M. C. Daly, J. Chorowicz, and J. D. Fairhead: Rift basin evolution in Africa: the influence of reactivated steep basement shear zones / Geological Society, London, Special Publications, 44:309-334, doi:10.1144/GSL.SP.1989.044.01.17 --- M. A. Cooper, G. D. Williams, P. C. de Graciansky, R. W. Murphy, T. Needham, D. de Paor, R. Stoneley, S. P. Todd, J. P. Turner, and P. A. Ziegler: Inversion tectonics — a discussion / Geological Society, London, Special Publications, 44:335-347, doi:10.1144/GSL.SP.1989.044.01.18 --- Abstracts --- I. W. D. Dalziel: Inversion of circum-Pacific marginal basins / Geological Society, London, Special Publications, 44:351, doi:10.1144/GSL.SP.1989.044.01.19 --- J. F. Dewey: Kinematics and dynamics of basin inversion / Geological Society, London, Special Publications, 44:352, doi:10.1144/GSL.SP.1989.044.01.20 --- A. Gibbs and A. Beach: Extensional tectonics in a convergent intra-plate setting: linked inversions on oblique and frontal ramps / Geological Society, London, Special Publications, 44:353, doi:10.1144/GSL.SP.1989.044.01.21 --- R. Gillcrist, M. P. Coward, B. Trudgill, A. Pecher, and J. L. Mugnier: Structural inversion in the external French Alps / Geological Society, London, Special Publications, 44:354, doi:10.1144/GSL.SP.1989.044.01.22 --- N. J. Kusznir and G. D. Williams: Geometric, thermal and isostatic constraints on basin inversion / Geological Society, London, Special Publications, 44:355, doi:10.1144/GSL.SP.1989.044.01.23 --- B. van Hoorn: Structural evolution, timing and tectonic style of the Sole Pit inversion / Geological Society, London, Special Publications, 44:356, doi:10.1144/GSL.SP.1989.044.01.24
    Pages: Online-Ressource (VII, 375 Seiten) , Illustrationen, Diagramme, Karten
    ISBN: 0632025026
    URL: http://sp.lyellcollection.org/content/44/1
    Language: English
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  • 4
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    Definition of a third VLR gene in hagfish [Immunology] (2013)
    National Academy of Sciences
    Details
    Publication Date: 2013-09-11
    Description: Jawless vertebrates (cyclostomes) have an alternative adaptive immune system in which lymphocytes somatically diversify their variable lymphocyte receptors (VLR) through recombinatorial use of leucine-rich repeat cassettes during VLR gene assembly. Three types of these anticipatory receptors in lampreys (VLRA, VLRB, and VLRC) are expressed by separate lymphocyte lineages. However, only...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 5
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    LAURENTIANITE, [NbO(H2O)]3(Si2O7)2[Na(H2O)2]3, A NEW MINERAL FROM MONT SAINT-HILAIRE, QUEBEC: DESCRIPTION, CRYSTAL-STRUCTURE DETERMINATION AND PARAGENESIS (2012)
    Mineralogical Association of Canada
    Details
    Publication Date: 2012-12-06
    Description: Laurentianite, [NbO(H 2 O)] 3 (Si 2 O 7 ) 2 [Na(H 2 O) 2 ] 3 , is a new mineral discovered in siderite-dominant pods in an altered syenite at the Poudrette quarry, Mont Saint-Hilaire, Quebec. Crystals are colorless, acicular, euhedral, and elongate along [001] with average dimensions of 0.012 x 0.012 x 0.25 mm. The mineral generally occurs in loose, randomly oriented groupings (‘nests’) of crystals. Associated minerals include quartz, pyrite, franconite, rutile, lepidochrocite, and an unidentified Fe-bearing mineral. Laurentianite is transparent to translucent with a vitreous luster and is non-fluorescent under long-, medium-, and short-wave radiation. The Mohs hardness could not be measured owing to the small size of the crystals. No partings or cleavages were observed, although crystals do exhibit a splintery fracture. The calculated density is 2.464 g/cm 3 . Laurentianite is nonpleochroic and uniaxial negative, with 1.612(2) and 1.604(2). The average of 12 analyses from several crystals is: Na 2 O 8.88 (4.54–12.80), K 2 O 0.26 (0.14–0.44), CaO 0.22 (0.10–0.43), TiO 2 0.58 (0.31–0.83), Nb 2 O 5 43.64 (36.43–49.90), SiO 2 26.87 (22.81–29.07), and H 2 O (calc.) 17.93, total 98.38 wt.% on the basis of 26 anions, corresponding to [(Nb 0.99 Ti 0.01 ) 1.00 O(H 2 O)] 3 (Si 2.00 O 7 ) 2 [(Na 0.86 0.10 K 0.02 Ca 0.01 ) 0.99 (H 2 O) 2 ] 3 or, ideally, [NbO(H 2 O)] 3 (Si 2 O 7 ) 2 [Na(H 2 O) 2 ] 3 . The presence of H 2 O in laurentianite is inferred from Raman spectroscopy and results from refinement of the crystal structure. The mineral crystallizes in space group P 3 (#143) with a 9.937(1), c 7.004(1) Å, V 599.0(1) Å 3 , and Z = 1. The strongest six lines on the X-ray powder-diffraction pattern [ d in Å (I) ( hkl )] are: 8.608 (100) (010), 7.005 (19) (001), 4.312 (25) (020), 3.675 (25) (201, 021), 3.260 (31) (120, 210), and 2.870 (20) (030). The crystal structure of laurentianite, refined to R = 2.78% for 2347 reflections ( F o 〉 4 F o ) contains one Na , two Nb , and four Si sites. The two Nb sites are coordinated in distorted Nb O 5 (H 2 O) octahedra, with four equatorial bonds of typical Nb–O bond distances (~2 Å) and two highly asymmetric ones (one long, ~2.5 Å and one short, ~1.8 Å). Each site is each only partially occupied (~50%) and because of the short distance between them (~0.7 Å), they are not simultaneously occupied. A novel cation-anion coordination scheme involving the apical oxygens, Nb, and disordered H 2 O groups is developed: when one of the Nb sites is occupied, the other is vacant, resulting in one of the apical O sites being occupied by O 2– and the other by H 2 O. The opposite situation occurs when the occupancy and vacancy of the Nb sites are reversed, leading to both apical O sites having an equal, mixed (O 2– /H 2 O) composition. A minor charge understaturation at both apical O sites is remedied by each of these O sites receiving a single H-bond from one of the H 2 O groups associated with the Na cation. The crystal structure of laurentianite is based on five-membered pinwheels of composition [Nb 3 Si 2 O 17 (H 2 O) 3 ] –11 , consisting of three Nb O 5 (H 2 O) octahedra linked to two SiO 4 tetrahedra. Individual Nb–Si pinwheels are attached to form a layer composed of 18-membered rings of composition [Nb 6 Si 12 O 54 (H 2 O) 6 ] 30– perpendicular to [001]. The crystal structure is also layered along [001], with a silicate layer composed of (Si 2 O 7 ) dimers and a layer of isolated Nb O 5 (H 2 O) octahedra. Sodium atoms are positioned within the silicate layer, occupying sites that almost directly overly the Nb sites but are displaced ~ z + 1/2. Laurentianite is a late-stage mineral intergrown with lepidocrocite, both of which overgrow franconite and quartz. The mineral is believed to have precipitated from a late-stage aqueous fluid enriched in Na, Si, and Nb, possibly arising through the breakdown of franconite, sodalite, and quartz.
    Print ISSN: 0008-4476
    Topics: Geosciences
    Published by Mineralogical Association of Canada
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  • 6
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    Krásnoite, the fluorophosphate analogue of perhamite, from the Huber open pit, Czech Republic and the Silver Coin mine, Nevada, USA (2012)
    Mineralogical Society of Great Britain and Ireland
    Details
    Publication Date: 2012-06-01
    Description: Krásnoite is a new mineral (IMA2011-040) from the Huber open pit, Krásno ore district, Czech Republic and the Silver Coin mine, Nevada, USA. Krásnoite is the fluorophosphate analogue of perhamite. Krásnoite occurs as compact to finely crystalline aggregates, balls and rosette-like clusters up to 1 mm across. Individual crystals are platy, show a hexagonal outline and can reach 0.1 mm on edge at Krásno and 0.4 mm at Silver Coin. At both localities, krásnoite occurs very late in phosphaterich paragenetic sequences. Krásnoite crystals are partly transparent with a typically pearly lustre, but can also appear greasy (Krásno) or dull (Silver Coin). The streak is white and the hardness is 5 on the Mohs scale. Crystals are brittle, have an irregular fracture, one imperfect cleavage on {001} and are not fluorescent under SW and LW ultraviolet light. Penetration twinning ⊥ {001} is common. The density for both Krásno and Silver Coin material is 2.48(4) g cm−3, measured by the sink–float method in an aqueous solution of sodium polytungstate. The calculated density is 2.476 g cm−3 (Krásno). Krásnoite crystals are uniaxial (+), with ω = 1.548(2) and ϵ = 1.549(2) (Krásno) and ω = 1.541(1) and ϵ = 1.543(1) (Silver Coin). The simplified formula of krásnoite is: Ca3Al7.7Si3P4O23.5(OH)12.1F2·8H2O. Krásnoite is trigonal, space group P3İm1, with a = 6.9956(4), c = 20.200(2) Å, V = 856.09(9) Å3 and Z = 3. Raman and infrared spectroscopy, coupled with magic-angle spinning nuclear magnetic resonance (MAS–NMR) spectrometry, confirmed the presence of PO3F, PO4, SiO4, H2O and OH in the crystal structure of krásnoite.
    Print ISSN: 0026-461X
    Electronic ISSN: 1471-8022
    Topics: Geosciences
    Published by Mineralogical Society of Great Britain and Ireland
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  • 7
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    Selection of the lamprey VLRC repertoire [Immunology and Inflammation] (2014)
    National Academy of Sciences
    Details
    Publication Date: 2014-10-15
    Description: The alternative adaptive immune system of jawless vertebrates is based on different isotypes of variable lymphocyte receptors (VLRs) that are composed of leucine-rich repeats (LRRs) and expressed by distinct B- and T-like lymphocyte lineages. VLRB is expressed by B-like cells, whereas VLRA and VLRC are expressed by two T-like lineages...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 8
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    Lagging adaptation to warming climate [Evolution] (2014)
    National Academy of Sciences
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    Publication Date: 2014-06-04
    Description: If climate change outpaces the rate of adaptive evolution within a site, populations previously well adapted to local conditions may decline or disappear, and banked seeds from those populations will be unsuitable for restoring them. However, if such adaptational lag has occurred, immigrants from historically warmer climates will outperform natives...
    Keywords: Inaugural Articles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 9
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    Set7 mediated interactions regulate transcriptional networks in embryonic stem cells (2016)
    Oxford University Press
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    Publication Date: 2016-11-01
    Description: Histone methylation by lysine methyltransferase enzymes regulate the expression of genes implicated in lineage specificity and cellular differentiation. While it is known that Set7 catalyzes mono-methylation of histone and non-histone proteins, the functional importance of this enzyme in stem cell differentiation remains poorly understood. We show Set7 expression is increased during mouse embryonic stem cell (mESC) differentiation and is regulated by the pluripotency factors, Oct4 and Sox2. Transcriptional network analyses reveal smooth muscle (SM) associated genes are subject to Set7-mediated regulation. Furthermore, pharmacological inhibition of Set7 activity confirms this regulation. We observe Set7-mediated modification of serum response factor (SRF) and mono-methylation of histone H4 lysine 4 (H3K4me1) regulate gene expression. We conclude the broad substrate specificity of Set7 serves to control key transcriptional networks in embryonic stem cells.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 10
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    S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA (2013)
    Oxford University Press
    Details
    Publication Date: 2013-03-23
    Description: Mutations in genes in the retinal pigment epithelium (RPE) cause or contribute to debilitating ocular diseases, including Leber's congenital amaurosis (LCA). Genetic therapies, particularly adeno-associated viruses (AAVs), are a popular choice for monogenic diseases; however, the limited payload capacity of AAVs combined with the large number of retinal disease genes exceeding that capacity make the development of alternative delivery methods critical. Here, we test the ability of compacted DNA nanoparticles (NPs) containing a plasmid with a scaffold matrix attachment region (S/MAR) and vitelliform macular dystrophy 2 (VMD2) promoter to target the RPE, drive long-term, tissue-specific gene expression and mediate proof-of-principle rescue in the rpe65 –/– model of LCA. We show that the S/MAR-containing plasmid exhibited reporter gene expression levels several fold higher than plasmid or NPs without S/MARs. Importantly, this expression was highly persistent, lasting up to 2 years (last timepoint studied). We therefore selected this plasmid for testing in the rpe65 –/– mouse model and observe that NP or plasmid VMD2-hRPE65-S/MAR led to structural and functional improvements in the LCA disease phenotype. These results indicate that the non-viral delivery of hRPE65 vectors can result in persistent, therapeutically efficacious gene expression in the RPE.
    Print ISSN: 0964-6906
    Electronic ISSN: 1460-2083
    Topics: Biology , Medicine
    Published by Oxford University Press
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