ISSN:
1573-8221
Keywords:
hypoxic preconditioning
;
pentoxifylline
;
α-tocopherol
;
reperfusion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Hypoxic preconditioning and pretreatment with pentoxifylline, α-tocopherol, or their combination promotes stabilization of Po2 in rabbit kidney cortex in the early reperfusion period (in experiments with α-tocopherol at a significantly lower level), while after 30-min reperfusion, the protective effect of α-tocopherol (especially in combination with pentoxifylline) markedly surpasses that of pentoxifylline and hypoxic preconditioning. α-Tocopherol sharply inhibits LPO in the reperfusion period, while pentoxifylline exhibits only weak antioxidant activity and hypoxic preconditioning was ineffective.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02433347
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