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  • Life and Medical Sciences  (372)
  • Chemical Engineering  (177)
  • Lunar and Planetary Science and Exploration
  • ASTROPHYSICS
  • 1995-1999  (716)
  • 1950-1954  (54)
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  • 1
    Publication Date: 2018-06-08
    Description: An engineering prototype linear ion trap frequency standar (LITS-4) using (sup 199)Hg+ is operational and currently under test for NASA's Deep Space Network (DSN). The DSN requires high stability and reliability with continuous operation.
    Keywords: Lunar and Planetary Science and Exploration
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  • 2
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 41 (1995), S. 1413-1425 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The adsorption of ethane from helium was measured in beds packed with 2.5 μm zeolite crystals and containing either a single hollow fiber or multiple fibers. THe single-fiber experiments indicate that the mass-transfer rate in bends containing zeolite 13X is limited by diffusion across the fiber wall and through macropores. FOr adsorption in single-fiber beds packed with zeolite 4A, mass transfer is limited by micropore diffusion within the particles. Breakthrough curves from beds containign 13X are adequately described with the linear driving force model, while curves from beds containing 4A are consistent with the Rosen model.Breakthrough curves from beds packed with zeolite 13X and containing multiple fibers can be predicted from the experiments with single-fiber beds when the fibers are evenly spaced. When fibers are unevenly spaced, the breakthrough curves are more disperse. Unevenly spaced fibers are the normal case. Even when fibers are evenly spaced, the productivity of hollow-fiber beds is expected to be no greater than that in conventional beds.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 43 (1997), S. 847-850 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
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  • 4
    ISSN: 0730-2312
    Keywords: osteocalcin ; transcriptional regulation ; homeodomain protein ; Msx ; bone-specific ; OC box ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Bone-specific expression of the osteocalcin gene is transcriptionally controlled. Deletion analysis of osteocalcin promoter sequences by transient transfection of osseous (ROS 17/2.8) and nonosseous (R2 fibroblast) cells revealed that the most proximal 108 nucleotides are sufficient to confer tissue-specific expression. By gel mobility shift assays with wild-type and mutated oligonucleotides and nuclear extracts from several different cell lines we identified a novel transcription factor complex which exhibits sequence-specific interactions with the primary transcriptional element, the OC box (nt -99 to -76). This OC box binding protein (OCBP) is present only in osteoblast-like cells. Methylation interference demonstrated association of the factor with OC box sequences overlapping the Msx homeodomain consensus binding site. By assaying several mutations of the OC box, both in gel shift and transient transfection studies using ROS 17/2.8, we show the following. First, binding of OCBP correlates with osteocalcin promoter activity in ROS 17/2.8 cells. Increased binding leads to a 2-3-fold increase in transcription, while decreased binding results in transcription 30-40% of control. Second, homeodomain protein binding suppresses transcription. However, Msx expression is critical for full development of the bone phenotype as determined by antisense studies. Last, we show that one of the mutations of the OC box permits expression of osteocalcin in non-osseous cell lines. In summary, we demonstrate association of at least two classes of tissue-restricted transcription factors with the OC box element, the OCBP and Msx proteins, supporting the concept that these sequences contribute to defining tissue specificity. © 1996 Wiley-Liss, Inc.
    Additional Material: 8 Ill.
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  • 5
    ISSN: 0730-2312
    Keywords: epitope mapping ; monoclonal antibodies ; linear epitope ; immuno-dominant ; immuno-recessive ; ELISA ; competitive ELISA ; recombinant GST-PSP94 ; N-terminal and C-terminal peptides ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: PSP94 has shown potential to be a serum biomarker for evaluating prostate cancer. Studies of the epitope structure is crucial for this endeavour. In this article, we have used 15 different monoclonal antibodies (MAb) to analyse the epitope structure of PSP94 and to compare with the results obtained from our previous work using polyclonal antibody and recombinant PSP94. Firstly, we determined the relative activities of the 15 MAb population by direct and competitive ELISA. The two predominant MAbs (MAb PSP-6 and -19) in 15 MAbs were selected for further studies of the epitope structure. By comparing the binding activities of recombinant GST-PSP94 and natural PSP94 with MAbs, and by comparing their affinity with MAbs in an in vitro denaturing experiment, PSP94 was shown to have a similar, prevalently linear epitope structure as we demonstrated by polyclonal antibody. Using recombinant GST fusion protein with PSP94 and with each half of the N- and C-terminal 47 amino acids (GST-PSP-N47/C47) in E. coli cells, the different epitopes recognized by 15 monoclonal antibodies were delineated and the polar distribution of the epitope structure of PSP94 was characterized. Results of direct ELISA of recombinant N47 and C47 and their competitive binding against natural PSP94 (competitive ELISA) showed that the N- and C-termini represent the immuno-dominant and immuno-recessive area separately. A majority of the monoclonal antibodies (12/15) showed preferential binding of the N-terminal sequence of the PSP94 protein. Using GST-PSP-N47 as a standard protein, an epitope map of the 15 monoclonal antibodies was obtained. The results of this study will help to define the clinical utility of PSP94. J. Cell. Biochem. 65:186-197. © 1997 Wiley-Liss, Inc.
    Additional Material: 8 Ill.
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  • 6
    ISSN: 0272-8397
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An investigation into the effect of isothermal aging on the development of transverse cracks in cross-ply laminates of two high temperature composite systems was performed. The composite materials investigated were BASF X5260/640-800 and DuPont Avimid K/IM6. Changes in the glass transition temperature, composite weight loss, crack density, and mode I intralaminar fracture toughness were monitored during isothermal aging in air at 177°C for up to 2232 h. The two laminate configurations used in this study include two variations of the generic cross-ply configuration [02/90n]s, in which n equals 1 and 2. The results of this investigation show that a layer of degraded material forms at the surface of the X5260/640-800 bismaleimide laminates and that the thickness of the degraded layer increases with aging time. After 744 h of aging, transverse cracks form in the surface plies and an increasing crack density evolves as aging time is increased; however, transverse cracks do not form in the inner 90° ply groups with aging during the time period investigated. The Avimid K/IM6 thermoplastic polyimide laminates, which show evidence of cracking prior to aging, do not exhibit any significant change in crack density with aging. The results of the aging experiments also show that the bismaleimide system exhibits a weight loss of 1.5% and an increase in glass transition temperature from 250°C to 300°C after 2232 h of aging at 177°C, while the thermoplastic polyimide system shows a weight loss of only 0.05% and an increase in glass transition temperature from 280 to 285°C after 2232 h. Changes in the resistance to crack formation are also seen in these materials during aging. The mode I intralaminar fracture toughness, a measure of resistance to transverse crack formation, shows a 50% decrease after aging for 2232 h for the bismaleimide system, while the behavior exhibited by the thermoplastic polyimide shows little evidence of a reduction.
    Additional Material: 8 Ill.
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  • 7
    Publication Date: 2011-08-24
    Description: It is often argued that substantially more carbon dioxide and water were degassed from the martian interior than can be found at present in the atmosphere, polar caps and regolith. Calculations have shown that atmospheric escape cannot account for all of the missing volatiles. Suggestions that carbon dioxide is stored as marine or lacustrine deposits, are challenged by Earth-based and spacecraft remote-sensing data. Moreover, recent modelling of the martian atmosphere suggests that rainfall or open bodies of water are in any case unlikely to have persisted for extended periods of time. Hydrothermal carbonates therefore provide a possible solution to this dilemma. Using an accessible terrestrial system (Iceland) as a guide to the underlying processes, and a host rock composition inferred from the least-altered martian meteorite, we present a geochemical model for the formation of carbonates in possible martian hydrothermal systems. Our results suggest that an extensive reservoir of carbonate minerals--equivalent to an atmospheric pressure of carbon dioxide of at least one bar--could have been sequestered beneath the surface by widespread hydrothermal activity in the martian past.
    Keywords: Lunar and Planetary Science and Exploration
    Type: Nature (ISSN 0028-0836); Volume 377; 6548; 406-8
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  • 8
    Publication Date: 2018-06-08
    Description: The Lunar Prospector (LP) spacecraft has provided the first polar low latitude measurement of the lunar gravity field and as a result gives significant improvement in the lunar gravity field model.
    Keywords: Lunar and Planetary Science and Exploration
    Type: Science
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  • 9
    Publication Date: 2019-07-13
    Description: We investigate spectral evolution in 37 bright, long gamma-ray bursts observed with the Burst and Transient Source Experiment (BATSE) spectroscopy detectors. High-resolution spectra are chracterized by the energy of the peak of nu F(sub nu), and the evolution of this quantity is examined relative to the emission intensity. In most cases it is found that this peak energy either rises with or slightly precedes major intensity increases and softens for the remainder of the pulse. Interpulse emission is generally harder early in the burst. For bursts with multiple intensity pulses, later spikes tend to be softer than earlier ones, indicating that the energy of the peak of nu F(sub nu) is bounded by an envelope which decays with time. Evidence is found that bursts in which the bulk of the flux comes well after the event which triggers the instrument tend to show less peak energy variability and are not as hard as several bursts in which the emission occurs promptly after the trigger. Several recently proposed burst models are examined in light of these results and no qualitative conflicts with the observations presented here are found.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 439; 1; p. 307-321
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  • 10
    Publication Date: 2019-08-28
    Description: The unusual variable star AM CVn has puzzled astronomers for over 40 years. This object, both a photometric and spectroscopic variable, is believed to contain a pair of hydrogen-deficient white dwarfs of extreme mass ratio, transferring material via an accretion disk. We examine the photometric properties of AM CVn, analyzing 289 hours of high-speed photometric data spanning 1976 to 1992. The power spectrum displays significant peaks at 988.7, 1248.8, 1902.5, 2853.8, 3805.2, 4756.5, and 5707.8 microHz (1011.4, 800.8, 525.6, 350.4, 262.8, 210.2, and 175.2 s). We find no detectable power at 951.3 microHz (1051 s), the previously reported main frequency. The 1902.5, 2853.9, and 3805.2 microHz peaks are multiplets, with frequency splitting in each case of 20.77 +/- 0.05 microHz. The 1902.5 microHz seasonal pulse shapes are identical, within measurement noise, and maintain the same amplitude and phase as a function of color. We have determined the dominant frequency to be 1902.50902 +/- 0.00001 microHz with dot P = +1.71 (+/- 0.04) x 10(exp -11) s/s. We discuss the implications of these findings on a model for AM CVn.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 445; 2; p. 927-938
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