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  • 11
    Online Resource
    Online Resource
    Pathophysiology of Obesity-Induced Health Complications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Human physiology. ; Human Physiology.
    Description / Table of Contents: Prevalence, consequences, causes and management of obesity -- Adipocytes Under Environmental Assault: Targets for Obesity? -- Obesity and its Complications Pathogenesis -- Extracellular Vesicles and Circulating miRNAs - Exercise -Induced Mitigation of Obesity and Associated Metabolic Diseases -- Pathophysiology of Obesity Induced Hyperglycemia and Insulin Resistance -- Obesity and Osteoarthritis: Are Adipokines Bridging Metabolism, Inflammation, and Biomechanics -- Understanding the Initiation and Progression of Diet-Induced Obesity and Associated Pathophysiology: Lessons Learned from a Rat Model -- Immune Modulation and Macrophage Polarization in Pathogenesis of Pancreatic Dysfunction in Obesity -- Association Between Obesity and Poor Sleep: A Review of Epidemiological Evidence -- Exploration of the Bidirectionality of Obesity and Depression by means of the Neuropsychological Model of Obesity Genesis -- Obesity-Induced Non-Alcoholic Fatty Liver Disease (NAFLD): role of hyperhomocystenemia -- Mechanisms of Obesity Related Kidney Disease -- Consequences of Maternal Obesity on Neonatal Outcomes and Cardio-Metabolic Health in Infancy -- The Developmental Mechanisms of Obesity by Maternal Obesity -- Diet Induced Maternal Hypercholesterolemia and In Utero Fetal Programming -- Modified Denouement in Bariatric Surgery due to Genetic Polymorphism -- Anti-Inflammatory Components from Functional Foods for Obesity -- Attenuation of Obesity-Associated Oxidative Stress by Cucurbita maxima Seed Oil in High Fat Diet Induced Obese Rats -- Pathophysiology of Obesity-Related Non-Communicable Chronic Diseases and Advancements in Preventive Strategies.
    Abstract: According to the World Health Organization, the epidemic of global obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults were overweight, over 650 million of which were obese. Being overweight and obese has been linked to a number of non-communicable, chronic diseases. Pathophysiology of Obesity-Induced Health Complications is a compilation of review articles dedicated to describe co-morbidities associated with obesity. The wide range that is covered is of significant interest to basic research scientists, clinicians and graduate students who are engaged in studying obesity-induced health complications. Furthermore, this book highlights the potential of novel approaches for the prevention and treatment of obesity and its related illnesses. Nineteen articles in this book are organized in four sections that are designed to provide an overview of obesity-induced health complications. The first section serves as an introductory section on the prevalence, causes, consequences, treatments and preventive approaches for obesity. Section two covers the metabolic disturbances and inflammation due to obesity. The third section is focused on neurological and visceral complications as a consequence of obesity. The final section covers strategies for the prevention of obesity-induced complications. The book illustrates that obesity can result in a diverse range of pathophysiological conditions that adversely affect health.
    Type of Medium: Online Resource
    Pages: XVI, 345 p. 40 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030353582
    Series Statement: Advances in Biochemistry in Health and Disease, 19
    URL: https://doi.org/10.1007/978-3-030-35358-2
    DOI: 10.1007/978-3-030-35358-2
    DDC: 612
    Language: English
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  • 12
    Online Resource
    Online Resource
    Cellular and Biochemical Mechanisms of Obesity (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Human physiology. ; Human Physiology.
    Description / Table of Contents: Cellular and biochemical mechanisms of obesity -- The role of inflammation in obesity -- Hypothalamic inflammation and malfunctioning glia in the pathophysiology of obesity -- The role of the inflammasome in obesity -- Adipose tissue macrophages and their polarization in health and obesity -- Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation -- The interplay between adipocytes and immune system cells in the pathophysiology of obesity -- Neuropeptides in Obesity and Metabolic Disease -- Adiposity and the Role of Neuroendocrine Hormones in Energy Balance -- Obesity in menopause -- Ovarian hormones and obesity -- The role of tissue-specific glucocorticoids in central obesity -- Thyroid function in obesity -- Glucocorticoid hormones: cause or cure for obesity -- Obesity: An overview of possible role(s) of gut hormones, lipid sensing and gut microbiota -- Recent advances in leptin and obesity -- Pathophysiology of obesity due to neurohormonal dysregulation and autophagy -- The Role of the Autonomic Nervous System in the Pathophysiology of Obesity -- Disturbance of neuronal signals in the pathophysiology of obesity -- The sympathetic neuro-adipose connection and the control of body weight -- Sympathetic activation in obesity -- Obesity-associated sympathetic overactivity in children and adolescents: the role of catecholamine resistance in lipid metabolism -- Relevance of Sympathetic Nervous System Activation in Obesity and Metabolic Syndrome -- Should the sympathetic nervous system be a target to improve obesity? -- Metabolic Syndrome and Oxidative Stress: A Complex Relationship -- The role of oxidative stress in the pathogenesis of obesity -- How effective are antioxidant supplements in obesity -- Oxidative stress in obesity: a critical component in human diseases -- Cellular mechanisms involved in the pathophysiology of obesity during oxidative stress -- Oxidative stress and metabolic pathologies: from an adipocentric point of view -- Oxidative stress contributes to the pathogenesis of obesity -- The genetics of oxidative stress in obesity -- Increased oxidative stress is associated with adipocyte fat accumulation -- The vicious cycle of oxidative stress and obesity -- GPCR-Mediated Signaling of Metabolites in the pathophysiology of obesity -- Ceramide signaling in obesity -- The role of the triggering receptor in the pathophysiology of obesity -- The AMPK pathway in the development of obesity -- Interleukin-1 superfamily: Divergent roles in obesity -- Ghrelin Receptor Mutations and Human Obesity -- Sirtuin 1 deacetylase: a key regulator of hepatic lipid metabolism -- JAK/STAT signaling pathway in the development of obesity -- SIRT1 and SIRT3 as mediators for the development of obesity -- Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity -- Interplay between Obesity and cGMP Signaling in adipose tissue.
    Abstract: Global health has been challenged with the dawning of the era of the obesity epidemic, and thus as a consequence, strategies to reduce obesity have become public health priorities. According to the United Nations, obesity has been identified as a concern for achieving Sustainable Development Goals. Obesity is a serious health problem with an increased risk of several common diseases including diabetes, cardiovascular disease, and cancer. Although the fundamental cause of obesity and overweight is an imbalance between calorie intake and calorie expenditure, the underlying biochemical and metabolic processes that cause obesity are not fully understood. Two earlier volumes dedicated to the subject of obesity, published in the series “Advances in Biochemistry in Health and Disease” focused on the pathophysiology of obesity-induced health complications and the biochemistry of cardiovascular dysfunction in obesity. This book brings together contributions from international experts in the field to describe advancements on the mechanisms leading to development of obesity and related complications. There are 21 chapters in two different parts in this book, comprising of Part I: Pathophysiologic Mechanisms of Obesity (11 chapters) and Part II: Therapeutic Mechanisms of Obesity (10 chapters). This book will serve as a resource and be of interest to health professionals, medical students, fellows, residents and graduate students. It will also evoke innovative research and effective approaches for the prevention of obesity. This volume will accentuate that obesity is a major health hazard in its own right and that appropriate public health measures should be implemented to prevent or reduce or even reverse the impact of this global chronic disease. .
    Type of Medium: Online Resource
    Pages: XVIII, 414 p. 72 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030847630
    Series Statement: Advances in Biochemistry in Health and Disease, 23
    URL: https://doi.org/10.1007/978-3-030-84763-0
    DOI: 10.1007/978-3-030-84763-0
    DDC: 612
    Language: English
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  • 13
    Online Resource
    Online Resource
    Cancer Metastasis Through the Lymphovascular System (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Metastasis. ; Lymphatics. ; Cancer Biology. ; Metastasis. ; Lymphatic System.
    Description / Table of Contents: Section 1: Genetic and Molecular Pathways of Cancer Growth and Metastasis -- Chapter 1. Hallmarks of Cancer: Molecular Underpinnings -- Chapter 2. Unifying concept of genomic changes: The mutational landscape of cancers -- Chapter 3. Tumor Microenvironment: Coconspirator in Tumorigenesis -- Chapter 4. Hallmarks of Metastasis: Molecular Underpinnings -- Chapter 5. Hereditary Cancer Syndromes and Cancer Metastasis -- Section 2: Pathology of Cancer Growth and Metastasis -- Chapter 6. Pathologic Assessment of Lymph Node Metastasis -- Chapter 7. Pathologic Assessment of Systemic or Distant Metastasis -- Chapter 8. The Role of Angiotropic Extravascular Migratory Metastasis in Metastases -- Section 3: Dormant Cancer Cells and their Reactivation in the Host Cancer Microenvironment -- Chapter 9. Tumor Dormancy and Relapse Regulated by the Extracellular Matrix -- Chapter 10. Therapy-Induced Dormancy and Residual Disease -- Section 4: The Microenvironment of Site-Specific Metastasis - Isaac P. Witz -- Chapter 11. The Microenvironment of Site-Specific Metastasis -- Section 5: Circulating Cancer Cells and Liquid Biopsy -- Chapter 12. Circulating tumor cells and ctDNA in sarcomas -- Chapter 13. Liquid biopsy using cell-free tumor DNA for gastrointestinal cancers -- Chapter 14. Circulating tumor cells and ctDNA in prostate cancer.-Chapter 15. Circulating Tumor Cells in Lung Cancer -- Chapter 16. CTCs/ ctDNA and Brain Metastasis.-Chapter 17. Epigenetics and liquid biopsy in oncology: role in metastasis and clinical utility -- Chapter 18. Metabolic reprogramming of circulating tumor cells for metastasis -- Section 6: Lymphatic System and Cancer Metastasis -- Chapter 19. Lymphatic System Biology, Pathobiology, and Relation to Cancer Metastasis -- Chapter 20. Lymphatic Specification and Development, EMT-MET, and Cancer Spread -- Chapter 21. Lymphangiogenesis, Lymph Nodes, Cancer Lymphangiogenesis and Metastasis -- Chapter 22. Immune cell trafficking in the lymphatics, hyaluronan biology and tumour metastasis -- Chapter 23. Lymphvascular Genomics and Proteomics, Clinical Syndromes, and Cancer Metastasis -- Chapter 24. Imaging of the Lymphatic System with Relevance to Cancer and Cancer Metastasis -- Chapter 25. Lymphedema: general pathophysiology, prevention and management in invasive cancer -- Section 7: Radiological Imaging of Early Cancer and Cancer Metastases -- Chapter 26. Primary Tumor Staging and Detection of Common Sites of Distant Metastatic Disease -- Chapter 27. Imaging Modalities in the Detection and Diagnosis of Metastatic Disease -- Chapter 28. Imaging of Bone Metastases -- Chapter 29. Imaging of Lung and Soft Tissue Metastases -- Chapter 30. Image-Guided Biopsy and Intervention for Metastatic Disease -- Section 8: Sentinel Lymph Node Surgery for Solid Cancer. Chapter 31. Sentinel Lymph Node Biopsy for Primary Cutaneous Malignancy -- Chapter 32. Sentinel Lymph Node Biopsy in Breast Cancer -- Chapter 33. Sentinel node navigation surgery for upper gastrointestinal cancer -- Chapter 34. Sentinel Lymph Node Mapping in Non-Small Cell Lung, Colon, and Thyroid Carcinomas -- Section 9: Surgical Treatment of Primary and Metastatic Cancer -- Chapter 35. The efficacy and evolution of surgical management based on cancer biology -- Chapter 36. The role of surgery in managing primary and metastatic melanoma -- Chapter 37. The Role of Surgery in Managing Primary and Metastatic Breast Cancer -- Chapter 38. The role of surgery in managing primary and metastatic colorectal cancer -- Chapter 39. The Role of Surgery in Management of Gastric Cancer -- Chapter 40. The role of surgery in managing primary and metastatic hepatopancreaticobiliary cancers -- Section 10: Cancer Metastasis to the Lung -- Chapter 41. Metastatic disease of the lung -- Section 11: Cancer Metastasis to the Liver -- Chapter 42. Tumor Resection and Ablation as a Means of Controlling Hepatic Metastases -- Chapter 43. Regional Arterial Infusional Therapy as a Means of Controlling Hepatic Metastases -- Section 12: Cancer Metastasis to the Bone -- Chapter 44. Molecular Mechanisms of Metastasis to the Bone.-Chapter 45. Surgical Management of Metastatic Disease to the Upper Extremity -- Chapter 46. Surgical Management of Metastatic Disease to the Lower Extremity -- Chapter 47. Surgical management of metastatic disease to the pelvis -- Chapter 48. Surgical Management of Metastatic Disease to the Spine -- Chapter 49. Interventional radiology techniques for management of skeletal metastases -- Section 13: Cancer Metastasis to the Brain and the Nervous System -- Chapter 50. Brain Metastases: Overview and Molecular Mechanisms -- Chapter 51. Indications and Techniques for Surgical Intervention in Patients with Metastatic Brain Tumors -- Chapter 52. Brain Metastases: Current and Future pharmacological treatment -- Chapter 53. Radiotherapy for CNS Metastases -- Chapter 54. Leptomeningeal Carcinomatoses -- Section 14: Urologic Cancer and 1st Patterns of Metastasis -- Chapter 55. Urologic Cancer and 1st Patterns of Metastasis -- Section 15: Biology and Clinical Aspects of Sarcoma Progression -- Chapter 56. Soft Tissue Sarcoma -- Chapter 57. Bone Sarcoma -- Chapter 58. Liposarcoma Metastasis -- Chapter 59. Desmoid Tumors.-Chapter 60. Atypical patterns of metastases: How do Sarcoma’s metastasize? -- Chapter 61. Tumor Immune Microenvironment of Soft Tissue Sarcoma -- Section 16: The Role of Radiation in the Treatment of Primary and Metastatic Cancer -- Chapter 62. Basic Principles of Radiobiology and Cancer Metastasis Prevention -- Chapter 63. Technical Innovations in the Delivery of Radiation Therapy -- Chapter 64. Radiation Therapy in the Definitive Treatment of Cancer -- Chapter 65. Radiation Therapy for Extracranial Oligometastatic Disease -- Chapter 66. Spine Radiotherapy -- Section 17: Immunotherapy of Solid Malignancies -- Chapter 67. Immunotherapy in Melanoma and Merkel Cell Cancer -- Chapter 68. Landscape of Immunotherapy in Lung Cancer -- Chapter 69. Immuno-oncologic Treatment of Genitourinary Malignancies -- Section 18: Current Topics -- Chapter 70. Personalized Systemic Cancer Therapy -- Chapter 71. Cancer Stem Cells and Their Role in Metastasis -- Chapter 72. HPV Induced Cancers -- Chapter 73. Microbiome and Cancer Metastasis -- Chapter 74. Application of Artificial Intelligence in Research on Cancer and Its Metastasis.
    Abstract: This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. .
    Type of Medium: Online Resource
    Pages: XXIV, 806 p. 145 illus., 106 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030930844
    URL: https://doi.org/10.1007/978-3-030-93084-4
    DOI: 10.1007/978-3-030-93084-4
    DDC: 571.978
    Language: English
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  • 14
    Online Resource
    Online Resource
    Biochemistry of Cardiovascular Dysfunction in Obesity (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Human physiology. ; Human Physiology.
    Description / Table of Contents: Biochemistry of cardiovascular dysfunction in obesity -- Vascular mechanisms linking RAAS components to obesity-associated hypertension -- Mechanisms of obesity-induced hypertension in adolescents -- Role of the sympathetic nervous system in obesity-induced hypertension -- Sex differences in the mechanisms associated with obesity-induced hypertension -- Leptin as a mediator of obesity-induced hypertension -- Endothelial dysfunction in obesity -- Neurohormonal regulation of sympathoexcitation and hypertension in obesity -- Role of obesity in hypertension in children -- Small for gestational age and obesity associated co-morbidities -- Obesity-Related Hypertension in Children -- The relationship between obesity and hypertension -- Hypertension in Obesity and the Impact of Weight Loss -- Parallels in the Evolution of Obesity and Hypertension -- Obesity and hypertension -- The microcirculation: a key player in obesity-associated cardiovascular disease -- Sex Differences in Leptin Control of Cardiovascular Function in Health and Metabolic Diseases -- Sex differences in the role of leptin and coronary heart disease -- Differential effect of subcutaneous abdominal and visceral adipose tissue on cardiometabolic risk -- Sex differences in lipid and lipoprotein metabolism -- Sex differences in the mechanisms of obesity-induced hypertension -- Impaired cardiac function in obese individuals -- Role of Vitamin D deficiency in cardiac function -- Obesity in advanced heart failure -- Cardiovascular morbidity and mortality associated with obesity -- Risk of overweight with the development of heart failure -- Obesity and heart failure -- Obesity phenotypes and their paradoxical association with cardiovascular diseases -- Mechanisms of heart failure with preserved ejection fraction in obesity -- Obesity and cardiovascular diseases -- Obesity and Heart Failure: Possible mechanisms of the Obesity Paradox -- Prognosis of morbid obesity patients with advanced heart failure -- BMI as a risk factor for cardiovascular disease -- Relationship between BMI and cardiovascular outcomes in diabetic patients -- Cardiometabolic risk in obese children -- Gender related differences in obesity associated cardiovascular complications -- Understanding the mechanisms and clinical significance of the obesity paradox -- Advances in understanding gender difference in cardiometabolic disease risk -- Cardiovascular and Metabolic Complications – Diagnosis and Management in Obese Children -- Obesity and Ventricular Repolarization.
    Abstract: Obesity is an independent risk factor for cardiovascular disease (CVD) in adults as well as in obese children. This book will provide a description of the impact of obesity on the cardiovascular system and increased predisposition to CVD. It will identify the major biochemical mechanisms that lead to the occurrence of myocardial abnormalities and vascular alterations in obesity. We will also have some discussion on the biochemistry of the so-called obesity paradox in relation to CVD. The contributors to this book are international experts on obesity and associated cardiovascular complications. This book is also uniquely positioned as it focuses on the biochemistry of obesity-induced cardiovascular dysfunction. There are 20 chapters in 2 different parts in this book, comprising of Part A: Pathophysiology of Cardiovascular Complications in Obesity (11 chapters) and Part B: Modification of Cardiovascular Dysfunction in obesity (9 chapters). The intent of this volume is to provide current and basic understanding of the biochemical mechanisms of obesity induced cardiovascular dysfunction that will be of value not only to cardiologists and other allied health professionals, but will also stimulate and motivate biomedical researchers and scientists to find the way to prevent the epidemic of obesity associated cardiovascular abnormalities. Furthermore, this book will serve as a highly useful resource for medical students, fellows, residents and graduate students with an interest in the cardiovascular system. In summary, this book covers a broad range of biochemical mechanisms of obesity-induced cardiovascular complications. We hope that the reader will understand that obesity is linked to an increase in the risk and occurrence of fatal CVD. Furthermore, the underlying message presented in the book is that the cause of obesity related disorders is complex and that understanding the biochemistry of cardiovascular dysfunction may contribute to the development of novel interventions for the prevention and treatment of obesity associated comorbidities.
    Type of Medium: Online Resource
    Pages: XV, 401 p. 55 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030473365
    Series Statement: Advances in Biochemistry in Health and Disease, 20
    URL: https://doi.org/10.1007/978-3-030-47336-5
    DOI: 10.1007/978-3-030-47336-5
    DDC: 612
    Language: English
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  • 15
    Online Resource
    Online Resource
    Pineal Neurosurgery (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Nervous system Surgery. ; Neurology . ; Neurosciences. ; Neurosurgery. ; Neurology. ; Neuroscience.
    Description / Table of Contents: Chapter 1 Embryology of the Pineal Gland -- Chapter 2 Anatomy of the Pineal Gland -- Chapter 3 Physiology of the Pineal Gland -- Chapter 4 Neuroimaging of the Pineal Gland -- Chapter 5 Tumors of the Pineal Gland -- Chapter 6 Non-tumorous Lesions of the Pineal Gland -- Chapter 7 Treatment and Approaches for the Pineal Gland Region -- Chapter 8 Interesting Cases of Pineal Gland Diseases and Surgery -- Chapter 9 Animal Based Surgical Training in Pineal Approaches -- Chapter 10 Evolutionary Retrace of the Third Eye.
    Abstract: This comprehensive book focuses on neurosurgical aspects of the pineal gland. By covering virtually all aspects of the pineal gland, it fills an important gap in the neurosurgical literature. Further, it approaches this vital component of the human brain from various angles: embryology, anatomy, physiology, pathology, radiology and surgical techniques. More than 70 single-best-answer multiple-choice questions (MCQs) are distributed throughout the chapters. Offering an essential review for residents and surgeons across neurosurgical disciplines and containing most of the critical information needed to prepare for both the primary and certification exam, the book will also be of interest to neurologists, neuroscientists and medical students. .
    Type of Medium: Online Resource
    Pages: XXVIII, 141 p. 42 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030531911
    URL: https://doi.org/10.1007/978-3-030-53191-1
    DOI: 10.1007/978-3-030-53191-1
    DDC: 617.48
    Language: English
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  • 16
    Online Resource
    Online Resource
    The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Human physiology. ; Cancer. ; Cancer Treatment. ; Virology. ; Therapeutics. ; Biomedical Research. ; Human Physiology. ; Cancer Biology. ; Cancer Therapy. ; Virology. ; Therapeutics.
    Description / Table of Contents: 1. Implications of renin-angiotensin system in health and disease -- 2. Renin angiotensin system and aging -- 3. The interplay of the renin-angiotensin system and solid organ transplantation -- 4. Correlation between renin angiotensin system and infectious disease -- 5. Emerging contributions of endocrine pathophysiology in virus-related infectious disease -- 6. Understanding the renin-angiotensin system in coronavirus disease 2019 -- 7. Metabolomics approach in differentiating RAS responses in ARDS (Acute respiratory distress syndrome) and SAR-CoV-2 -- 8. A Comprehensive review of the impact of the renin angiotensin system in the liver, lung, infectious diseases and cancers -- 9. Application of biosensors for monitoring changes in renin angiotensin system (RAS) in cancers and lung diseases -- 10. Bioinformatics study on renin angiotensin in lung, and liver cancer using plant-based extracts -- 11. Role of renin-angiotensin system in the pathogenesis and progression of non-alcoholic fatty liver -- 12. The classical and nonclassical renin-angiotensin-aldosterone system in liver cirrhosis -- 13. Renin-angiotensin-aldosterone system role in organ fibrosis -- 14. Role of renin angiotensin-aldosterone system in kidney homeostasis -- 15. Renin-angiotensin system in chronic kidney disease: Implications in stroke outcome -- 16. The renin-angiotensin system and cancer -- 17. Renin-angiotensin system and cancer: From laboratory to clinics -- 18. Role of renin-angiotensin system in cancer cachexia -- 19. Renin angiotensin system activity in different cancers: Mechanistic insight and preclinical studies -- 20. The new dimension of the renin-angiotensin system in the hallmarks of cancer -- 21. Renin-angiotensin system in hematological malignancies -- 22. Renin angiotensin system (RAS): The common thread between cancer and heart failure -- 23. Renin-angiotensin system: a potential therapeutic target for colorectal cancer -- 24. Anticancer role of natural phenolic acids by targeting angiotensin-converting enzyme (ACE) -- 25. Angiotensin-(1-7): A Prospective Cancer Therapeutic.
    Abstract: This book of the series on “Advances in Biochemistry in Health and Disease” includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.
    Type of Medium: Online Resource
    Pages: XX, 498 p. 70 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031236211
    Series Statement: Advances in Biochemistry in Health and Disease, 25
    URL: https://doi.org/10.1007/978-3-031-23621-1
    DOI: 10.1007/978-3-031-23621-1
    DDC: 610.72
    Language: English
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  • 17
    Online Resource
    Online Resource
    Agriculture, Livestock Production and Aquaculture : Advances for Smallholder Farming Systems Volume 1 (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Agriculture. ; Food security. ; Sustainability. ; Environmental Sciences. ; Agriculture. ; Food Security. ; Sustainability.
    Description / Table of Contents: Chapter1. Impact of future climate change on Agriculture, Livestock Production and Aquaculture: Challenges and Policy -- Chapter2. Managing agricultural nitrogen losses in crop production and mitigation of climate change effects -- Chapter3. Critical analysis and evaluation of groundnut value chain for revamping its production for global food security -- Chapter4. Aluminum uptake, callose accumulation and invertase activity in lowland and upland rice genotypes in related to aluminum stress tolerance -- Chapter5. Gender issues in farming — Challenging socially embedded positions in agrarian context -- Chapter6. Characterization and Appraisal of Crop based Farming System for Sustainable Development of Agriculture -- Chapter7. Nitrogen based for farming system -- Chapter8. Resilience for salt tolerance in rice cultivars using various strategies of conventional breeding, molecular breeding and transgenic approaches -- Chapter9. Geoinformation for land suitability modelling for climate smart farming in Africa -- Chapter10. Climate Change Adaptation: Remote Sensing-based Flood Crop Loss Assessment to Support Crop Insurance -- Chapter11. Smallholder Pig value chains development and livelihood security -- Chapter12. Revolutionizing impact of poultry resources in food security and rural economy -- Chapter13. Milk and Milk Product Safety and Quality Assurance for Achieving Better Public Health Outcomes -- Chapter14. Diversification in Aquaculture Resources and Practices for Smallholder Farmers -- Chapter15. Value addition in meat and fish products for human health and nutrition -- Chapter16. Indian Fish as Bioindicators species -- Chapter17. Conclusion. .
    Abstract: This two-volume set discusses recent approaches and technological innovations for sustainable agriculture in smallholder farming systems impacted by climate change. The systems covered include crop-based agricultural production, as well as aquaculture and livestock production as related systems using similar techniques to combat food security issues brought about by climate change and resource overuse. The chapters detail innovations involving crop diversification, soil resilience management, geoinformatics and land suitability monitoring for smart farming, information technology in livestock production, and nutrient resource management in fishery aquaculture. Researchers, practitioners and industries will be able to use this information to implement socially and economically sustainable practices to achieve food security in impoverished areas vulnerable to climate change, while also learning about the rapid evolution in information technology that is applicable for and available to small holder farmers. Volume 1 focuses on current innovations in agricultural and livestock practices in response to climate change. It covers the technological challenges, approaches and mitigation strategies encountered by both scholars and practitioners working in livestock and agricultural production systems impacted by climate change.
    Type of Medium: Online Resource
    Pages: XIII, 346 p. 69 illus., 57 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030932589
    URL: https://doi.org/10.1007/978-3-030-93258-9
    DOI: 10.1007/978-3-030-93258-9
    DDC: 333.7
    Language: English
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  • 18
    Online Resource
    Online Resource
    Agriculture, Livestock Production and Aquaculture : Advances for Smallholder Farming Systems Volume 2 (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Agriculture. ; Food security. ; Sustainability. ; Environmental Sciences. ; Agriculture. ; Food Security. ; Sustainability.
    Description / Table of Contents: Chapter1. Drone Technology in Sustainable Agriculture: The future of farming is precision agriculture and mapping -- Chapter2. Revolutionizing Crops and Soil Resources’ Resilience to Climate Change. A case for Best-fit Agronomic Practices in Low and High Input Systems -- Chapter3. Drought-resilient climate smart sorghum varieties for food and industrial use in marginal frontier areas of Kenya -- Chapter4. Optimizing nitrogen management for improved productivity, nitrogen use efficiency, food and nutrition security: African context perspectives -- Chapter5. Soil carbon pools under different farming practices -- Chapter6. Effect of conservation agriculture on energy consumption and carbon emission -- Chapter7. Plant Molecular Farming: A Marvelous Biotechnological Approach in Agricultural Production -- Chapter8. Examining the outcome of coupling machine learning with dual Polarimetric SAR for rice growth mapping -- Chapter9. Mapping prominent cash crops employing ALOS PALSAR-2 and selected machine learners -- Chapter10. Crop assessment and decision support information products using multi-sensor and multi-temporal moderate resolution data -- Chapter11. Agriculture, Livestock Production and Aquaculture: Advances for Smallholder Farming System -- Chapter12. Mobilizing Pig Resources for Capacity Development and Livelihood Security -- Chapter13. Agricultural Value Chains: A Cardinal Pillar for Future Development and Management of Farming -- Chapter14. Climate Smart Eco-management of Water and Soil Quality as a Tool for Fish Productivity Enhancement -- Chapter15. Advances in nutrient resource management for fisheries and aquaculture -- Chapter16. Conclusion.
    Abstract: This two-volume set discusses recent approaches and technological innovations for sustainable agriculture in smallholder farming systems impacted by climate change. The systems covered include crop-based agricultural production, as well as aquaculture and livestock production as related systems using similar techniques to combat food security issues brought about by climate change and resource overuse. The chapters detail innovations involving crop diversification, soil resilience management, geoinformatics and land suitability monitoring for smart farming, information technology in livestock production, and nutrient resource management in fishery aquaculture. Researchers, practitioners and industries will be able to use this information to implement socially and economically sustainable practices to achieve food security in impoverished areas vulnerable to climate change, while also learning about the rapid evolution in information technology that is applicable for and available to small holder farmers. Volume 2 focuses on trends and technologies in food security within the context of sustainable practices, drone technology, microwave data, molecular farming, machine learning, agricultural economics, spatial modeling and agricultural policy. These chapters discuss advancements in fishery resource and aquaculture practices, and also the challenges facing these areas due to climate change. .
    Type of Medium: Online Resource
    Pages: XV, 321 p. 79 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030932626
    URL: https://doi.org/10.1007/978-3-030-93262-6
    DOI: 10.1007/978-3-030-93262-6
    DDC: 333.7
    Language: English
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    Fluvial sedimentary structures formed experimentally in a pipe, and their implications for interpretation of subglacial sedimentary environments (1972)
    Ottawa : Geological Survey of Canada
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    Call number: SR 90.0008(72-27)
    In: Paper
    Type of Medium: Series available for loan
    Pages: IV, 30 S.
    Series Statement: Paper / Geological Survey of Canada 72-27
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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    The Hanklit glaciotectonic Thrust Fault Complex, Mors, Denmark (1995)
    Copenhagen : Geological Survey of Denmark
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    Call number: SR 91.1185(35)
    In: Danmarks Geologiske Undersoegelse. Serie A
    Type of Medium: Series available for loan
    Pages: 30 S.
    ISBN: 8789813235
    Series Statement: Danmarks Geologiske Undersoegelse : Serie A 35
    Language: English
    Location: Lower compact magazine
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