ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A systematic study on the relationship between the substitution pattern, the pKa values, and spectral properties of flavylium cations and the respective-(CH2)2-bridged analoga (5,6-dihydrobenzo[c]xanthylium cations) is given in order to find rules concerning their spectral behaviour and their chemical reactivity.Our results show that the concept of chemical hardness can explain the different reactivity of 4′- and 7-substituted flavylium ions against HO-. The pKa values of these species, which can act as a measure of reactivity with respect to a nucleophile, correlate linearly with the absolute hardness calculated from half the energy gap between the frontier orbitals. Since the longest-wavelength UV/VIS absorption maximum is mainly determined by the HOMO-LUMO transition, an analogous linear correlation is obtained between the spectral 0-0 transition and the pKa value. Deviations from these correlations are assumed to be due to steric effects.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.199633801142
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