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  • 11
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    Efficient hemodynamic event detection utilizing relational databases and wavelet analysis (2001)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: Development of a temporal query framework for time-oriented medical databases has hitherto been a challenging problem. We describe a novel method for the detection of hemodynamic events in multiparameter trends utilizing wavelet coefficients in a MySQL relational database. Storage of the wavelet coefficients allowed for a compact representation of the trends, and provided robust descriptors for the dynamics of the parameter time series. A data model was developed to allow for simplified queries along several dimensions and time scales. Of particular importance, the data model and wavelet framework allowed for queries to be processed with minimal table-join operations. A web-based search engine was developed to allow for user-defined queries. Typical queries required between 0.01 and 0.02 seconds, with at least two orders of magnitude improvement in speed over conventional queries. This powerful and innovative structure will facilitate research on large-scale time-oriented medical databases.
    Keywords: Life Sciences (General)
    Type: Computers in cardiology (ISSN 0276-6574); 28; 153-6
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  • 12
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    MIMIC II: a massive temporal ICU patient database to support research in intelligent patient monitoring (2002)
    In:  Other Sources
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    Publication Date: 2019-07-13
    Description: Development and evaluation of Intensive Care Unit (ICU) decision-support systems would be greatly facilitated by the availability of a large-scale ICU patient database. Following our previous efforts with the MIMIC (Multi-parameter Intelligent Monitoring for Intensive Care) Database, we have leveraged advances in networking and storage technologies to develop a far more massive temporal database, MIMIC II. MIMIC II is an ongoing effort: data is continuously and prospectively archived from all ICU patients in our hospital. MIMIC II now consists of over 800 ICU patient records including over 120 gigabytes of data and is growing. A customized archiving system was used to store continuously up to four waveforms and 30 different parameters from ICU patient monitors. An integrated user-friendly relational database was developed for browsing of patients' clinical information (lab results, fluid balance, medications, nurses' progress notes). Based upon its unprecedented size and scope, MIMIC II will prove to be an important resource for intelligent patient monitoring research, and will support efforts in medical data mining and knowledge-discovery.
    Keywords: Cybernetics, Artificial Intelligence and Robotics
    Type: Computers in cardiology (ISSN 0276-6574); 29; 641-4
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  • 13
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    Development of an Integrated Countermeasure Device for Use in Long-Duration Space Flight (2010)
    In:  CASI
    Details
    Publication Date: 2019-07-19
    Description: Prolonged weightlessness is associated with declines in musculoskeletal, cardiovascular, and sensorimotor health. Consequently, in-flight countermeasures are required to preserve astronaut health. We developed and tested a novel exercise countermeasure device (CCD) for use in spaceflight with the aim of preserving musculoskeletal and cardiovascular health along with an incorporated balance-training component. Additionally, the CCD features a compact footprint, and a low power requirement. Methods: After design and development of the CCD, we carried out a training study to test its ability to improve cardiovascular and muscular fitness in healthy volunteers. Fourteen male and female subjects (41.4+/-9.0 years, 69.5+/-15.4Kg) completed 12 weeks (3 sessions per week) of concurrent strength and endurance training on the CCD. Subjects were tested at baseline and after 12 weeks for 1-repetition max leg press strength (1RM), peak oxygen consumption (VO2peak), and isokinetic joint torque (ISO) at the hip, knee, and ankle. Additionally, we evaluated subjects after 6 weeks of training for changes in VO2peak and 1RM. Results: VO2peak and 1RM improved after 6-weeks, with additional improvements after 12 weeks (1.95+/-0.5, 2.28+/-0.5, 2.47+/-0.6 LY/min and 131.2+/-63.9,182.8+/-75.0, 207.0+/-75.0 Kg) for baseline, 6 weeks, and 12 weeks respectively. ISO for hip adduction, adduction, and ankle plantar flexion improved after 12 weeks of training (70.3+/-39.5, 76.8+/-39.2 and 55.7+/-21.7 N-m vs. 86.1+/-37.3, 85.1+/-34.3 and 62.1+/-26.4 N-m respectively). No changes were observed for ISO during hip flexion, knee extension, or knee flexion. Conclusions: The CCD is effective at improving cardiovascular fitness and isotonic leg strength in healthy adults. Further, the improvement in hip adductor and abductor torque provides support that the CCD may provide additional protection for the preservation of bone health at the hip.
    Keywords: Aerospace Medicine
    Type: JSC-CN-21987
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  • 14
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    Real-Time, High-Frequency QRS Electrocardiograph (2003)
    In:  CASI
    Details
    Publication Date: 2019-07-12
    Description: An electronic system that performs real-time analysis of the low-amplitude, high-frequency, ordinarily invisible components of the QRS portion of an electrocardiographic signal in real time has been developed. Whereas the signals readily visible on a conventional electrocardiogram (ECG) have amplitudes of the order of a millivolt and are characterized by frequencies 〈100 Hz, the ordinarily invisible components have amplitudes in the microvolt range and are characterized by frequencies from about 150 to about 250 Hz. Deviations of these high-frequency components from a normal pattern can be indicative of myocardial ischemia or myocardial infarction
    Keywords: Aerospace Medicine
    Type: MSC-23154 , NASA Tech Briefs, July 2003; 5-6
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  • 15
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    Real-time, high frequency QRS electrocardiograph (2006)
    In:  CASI
    Details
    Publication Date: 2019-08-28
    Description: Real time cardiac electrical data are received from a patient, manipulated to determine various useful aspects of the ECG signal, and displayed in real time in a useful form on a computer screen or monitor. The monitor displays the high frequency data from the QRS complex in units of microvolts, juxtaposed with a display of conventional ECG data in units of millivolts or microvolts. The high frequency data are analyzed for their root mean square (RMS) voltage values and the discrete RMS values and related parameters are displayed in real time. The high frequency data from the QRS complex are analyzed with imbedded algorithms to determine the presence or absence of reduced amplitude zones, referred to herein as RAZs. RAZs are displayed as go, no-go signals on the computer monitor. The RMS and related values of the high frequency components are displayed as time varying signals, and the presence or absence of RAZs may be similarly displayed over time.
    Keywords: Life Sciences (General)
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  • 16
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    On the aerodynamics and performance of active vortex generators (1993)
    In:  Other Sources
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    Publication Date: 2019-08-28
    Description: As a building block in the development of smart lift-enhancement devices, a new concept for flow control using active vortex generators (AVGs) is presented. Ramp, wedge, and doublet wedge (Wheeler) VG configurations are investigated. The AVGs are designed to conform to the surface of the wing section at low alpha. As the section approaches the stall, they are deployed and accordingly, alpha(stall) and C(lmax) are increased. A qualitative analysis of the flow around the various VG configurations was conducted in a low speed wind tunnel at 1.6 ft/s and a Reynolds number of approximately 3400. The results demonstrate that ramp VGs produce vortices that have the longest distance at breakdown. The VGs were also applied to a 25-in. span, 8-in. chord NACA 4415 wing section. Optimization studies were conducted on the spanwise spacing, chordwise position, and size of statically deployed VGs. The test results demonstrate a 14-percent increase in C(lmax) while increasing alpha (stall) by up to 3.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 93-3447 , In: AIAA Applied Aerodynamics Conference, 11th, Monterey, CA, Aug. 9-11, 1993, Technical Papers. Pt. 1 (A93-47201 19-02); p. 376-386.
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  • 17
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    An Integrated Musculoskeletal Countermeasure Battery for Long-Duration Lunar Missions (2011)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: During extended periods of skeletal unloading, losses in strength and density of the proximal femur will occur. In long-duration spaceflight, resistive exercise is used to replace the normal loads exerted on the spine and hip. At the present time, there is no conclusive evidence that hip bone loss has been prevented in this scenario. Our group has recently developed and clinically evaluated a multifunctional exercise system, the Combined Countermeasure Device (CCD). The CCD comprises a low-footprint Stuart Platform for lower-body resistance exercise and balance training, and a cardiovascular exercise bicycle. A consideration for resistance exercise was targeting of the hip abductor and adductor muscles, which attach directly at the hip and which should subject it to the largest loads. In our training study, we found that CCD exercise increased hip adductor and abductor strength, and modeling results suggest that this exercise exerts forces on the hip of approx. 4-6 body weights at 1g, compared to forces of approx.2.5 body weight y squatting exercise. In our current study, we hypothesize that abductor and adductor exercise will increase the density and strength of the proximal femur.
    Keywords: Aerospace Medicine
    Type: JSC-CN-25294 , 2012 NASA Human Research Program Investigators'' Workshop; Feb 14, 2012 - Feb 16, 2012; Houston, TX; United States
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  • 18
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    Power SiGe Heterojunction Bipolar Transistors (HBTs) Fabricated by Fully Self-Aligned Double Mesa Technology (2001)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: Multifinger SiGe HBTs have been fabricated using a novel fully self-aligned double-mesa technology. With the novel process technology, a common-emitter 2x2x30 sq micrometer device exhibits high maximum oscillating frequency (f(sub max)) and cut-off frequency (f(sub T)) of 78 and 37 GHz, respectively. In class-A operation, a multifinger device with l0x2x30 sq micrometer emitter is expected to provide an output power of 25.6 dBm with a gain of 10 dB and a maximum power added efficiency (PAE) of 30.33% at 8 GHz.
    Keywords: Electronics and Electrical Engineering
    Type: IEEE MTT-S International Microwave Symposium; May 20, 2001 - May 25, 2001; Phoenix, AZ; United States
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  • 19
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    The Effects of the Critical Ice Accretion on Airfoil and Wing Performance (1998)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: In support of the NASA Lewis Modern Airfoils Ice Accretion Test Program, the University of Illinois at Urbana-Champaign provided expertise in airfoil design and aerodynamic analysis to determine the aerodynamic effect of ice accretion on modern airfoil sections. The effort has concentrated on establishing a design/testing methodology for "hybrid airfoils" or "sub-scale airfoils," that is, airfoils having a full-scale leading edge together with a specially designed and foreshortened aft section. The basic approach of using a full-scale leading edge with a foreshortened aft section was considered to a limited extent over 40 years ago. However, it was believed that the range of application of the method had not been fully exploited. Thus a systematic study was being undertaken to investigate and explore the range of application of the method so as to determine its overall potential.
    Keywords: Air Transportation and Safety
    Type: NASA/CR-96-207501 , NAS 1.26:207501
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  • 20
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    A study of three dimensional turbulent boundary layer separation and vortex flow control using the reduced Navier Stokes equations (1991)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: A reduced Navier Stokes (RNS) initial value space marching solution technique was applied to vortex generator and separated flow problems and demonstrated good predictions of the engine face flow field. This RNS solution technique using FLARE approximations can adequately describe the topological and topographical structure flow separation associated with vortex liftoff, and this conclusion led to the concept of a subclass of separations which can be called vorticity separations: separations dominated by the transport of vorticity. Adequate near wall resolution of vorticity separations appears necessary for good predictions of these flows.
    Keywords: AERODYNAMICS
    Type: NASA-TM-104407 , E-6233 , NAS 1.15:104407 , Turbulent Shear Flow Symposium; Sep 09, 1991 - Sep 11, 1991; Munich; Germany
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